(define (problem Pathways-14)
(:domain Pathways-ComplexPreferences)
(:objects
	Wee1 - simple
	SP1 - simple
	Skp2 - simple
	RPA - simple
	pRb-E2F4p1-DP12 - simple
	pRb - simple
	Plk1 - simple
	p57 - simple
	p53p1 - simple
	p53 - simple
	p27 - simple
	Max - simple
	m1433 - simple
	Jun - simple
	HDAC1-pRbp1-E2F13p1-DP12 - simple
	HDAC1-pRbp1-E2F13-DP12 - simple
	HDAC1-p130-E2F4p1-DP12 - simple
	HDAC1-p107-E2F4p1-DP12 - simple
	HDAC1 - simple
	gp19ARF - simple
	gERCC1 - simple
	gE-c - simple
	gE2 - simple
	E2F13p1-DP12p1 - simple
	E2F13p1-DP12 - simple
	E2F13-DP12p1 - simple
	E2F13-DP12 - simple
	E2F13 - simple
	DMP1 - simple
	cycH - simple
	cycB - simple
	C-TAK1 - simple
	cks1 - simple
	Chk1 - simple
	cdk7 - simple
	cdk46p3-cycDp1 - simple
	cdk2p2-cycB - simple
	cdk2p1 - simple
	cdk1p1p2 - simple
	cdc25C - simple
	c-Abl - simple
	APC - simple
	AP2 - simple
	AP2-gE-c - complex
	c-Abl-pRb - complex
	c-Abl-pRbp1 - complex
	cdk1-cks1 - complex
	cdk1-Gadd45 - complex
	cdk1p1-cks1 - complex
	cdk1p1-Gadd45 - complex
	cdk1p1 - complex
	cdk1p1p2-cks1 - complex
	cdk1p1p2-Gadd45 - complex
	cdk1p1p2p3-cks1 - complex
	cdk1p1p2p3-Gadd45 - complex
	cdk1p1p2p3 - complex
	cdk1p1p3-cks1 - complex
	cdk1p1p3-Gadd45 - complex
	cdk1p1p3 - complex
	cdk1 - complex
	cdk1p2-cks1 - complex
	cdk1p2-Gadd45 - complex
	cdk1p2 - complex
	cdk1p2p3-cks1 - complex
	cdk1p1p2p3-cycA - complex
	cdc25Cp1 - complex
	cdk1p1p2p3-cycB - complex
	cdk1p2p3-Gadd45 - complex
	cdk1p2p3 - complex
	cdk1p3-cks1 - complex
	cdk1p1p3-cycA - complex
	cdk1p2p3-cycA - complex
	cdk1p1p3-cycB - complex
	cdk1p2p3-cycB - complex
	cdk1p3-Gadd45 - complex
	cdk1p3 - complex
	cdk2p1-cks1 - complex
	cdk2p1-cycA-E2F13 - complex
	cdk2p1p2-cks1 - complex
	cdk2p1p2-cycA-E2F13 - complex
	cdk2p1p2 - complex
	cdk2p1p2-cycB - complex
	cdk7-cycH - complex
	cdk7p1-cycH - complex
	c-Myc-AP2 - complex
	c-Myc-Max - complex
	APCp1 - complex
	DMP1-cycD - complex
	DMP1-cycDp1 - complex
	DMP1-gp19ARF - complex
	DMP1p1-cycD - complex
	DMP1p1-cycDp1 - complex
	DMP1p1 - complex
	DMP1p1-gp19ARF - complex
	E2F13-DP12-gE2 - complex
	E2F13p1-DP12-gE2 - complex
	HDAC1-p107-E2F4p1-DP12-gE2 - complex
	HDAC1-p130-E2F4p1-DP12-gE2 - complex
	HDAC1-pRb-E2F13-DP12-gE2 - complex
	HDAC1-pRb-E2F13-DP12 - complex
	HDAC1-pRb-E2F13-DP12p1 - complex
	HDAC1-pRb-E2F13p1-DP12-gE2 - complex
	HDAC1-pRb-E2F13p1-DP12 - complex
	HDAC1-pRb-E2F13p1-DP12p1 - complex
	HDAC1-pRb-E2F4p1-DP12 - complex
	HDAC1-pRbp1-E2F13-DP12-gE2 - complex
	HDAC1-pRbp1-E2F13p1-DP12-gE2 - complex
	Jun-c-Fos-gERCC1 - complex
	Jun-c-Fos - complex
	m1433-cdc25Cp1p2 - complex
	cdc25Cp1p2 - complex
	m1433-cdc25Cp2 - complex
	cdc25Cp2 - complex
	Mdm2-E2F13-DP12 - complex
	Mdm2-E2F13-DP12p1 - complex
	Mdm2-E2F13p1-DP12 - complex
	Mdm2-E2F13p1-DP12p1 - complex
	Mdm2-pRb - complex
	Mdm2-pRbp1 - complex
	cdk7p1 - complex
	p21-cdk2p1-cycA - complex
	p21-cdk2p1-cycEp1 - complex
	p21-cdk2p1-cycE - complex
	p21-cdk2p1p2-cycA - complex
	p21-cdk2p1p2-cycEp1 - complex
	p21-cdk2p1p2-cycE - complex
	p21-Gadd45 - complex
	p27-cdk2p1-cycA - complex
	p27-cdk2p1-cycEp1 - complex
	p27-cdk2p1-cycE - complex
	p27-cdk2p1p2-cycA - complex
	p27-cdk2p1p2-cycEp1 - complex
	p27-cdk2p1p2-cycE - complex
	Mdm2 - complex
	p57-cdk2p1-cycA - complex
	p57-cdk2p1-cycEp1 - complex
	p57-cdk2p1-cycE - complex
	p57-cdk2p1p2-cycA - complex
	p57-cdk2p1p2-cycEp1 - complex
	p57-cdk2p1p2-cycE - complex
	Gadd45 - complex
	cdk2p1-cycEp1 - complex
	cdk2p1-cycE - complex
	cdk2p1p2-cycEp1 - complex
	cdk2p1p2-cycE - complex
	p21 - complex
	pRb-AP2-gE-c - complex
	pRb-AP2 - complex
	pRb-E2F13-DP12-gE2 - complex
	pRb-E2F13-DP12p1-gE2 - complex
	pRb-E2F13p1-DP12-gE2 - complex
	pRb-E2F13p1-DP12p1-gE2 - complex
	pRb-E2F4p1-DP12-gE2 - complex
	pRb-Jun-c-Fos-gERCC1 - complex
	pRb-Jun-c-Fos - complex
	pRb-Jun - complex
	pRbp1-AP2-gE-c - complex
	pRbp1-AP2 - complex
	pRbp1-E2F13-DP12-gE2 - complex
	pRbp1-E2F13-DP12p1-gE2 - complex
	pRbp1-E2F13p1-DP12-gE2 - complex
	pRbp1-E2F13p1-DP12p1-gE2 - complex
	pRbp1-Jun-c-Fos-gERCC1 - complex
	pRbp1-Jun-c-Fos - complex
	pRbp1-Jun - complex
	pRbp1 - complex
	Ecadherin - complex
	ERCC1 - complex
	c-Fos - complex
	pRb-E2F13-DP12p1 - complex
	pRb-E2F13-DP12 - complex
	pRb-E2F13p1-DP12p1 - complex
	pRb-E2F13p1-DP12 - complex
	pRbp1-E2F13-DP12p1 - complex
	pRbp1-E2F13-DP12 - complex
	pRbp1-E2F13p1-DP12p1 - complex
	pRbp1-E2F13p1-DP12 - complex
	RPA-cycA - complex
	Skp2-cdk2p1-cycA - complex
	Skp2-cdk2p1p2-cycA - complex
	cdk2p1-cycA - complex
	cdk2p1p2-cycA - complex
	SP1-E2F13 - complex
	c-Myc - complex
	cycA - complex
	cycD - complex
	cycDp1 - complex
	cycE - complex
	cycEp1 - complex
	p19ARF - complex
	pol - complex
	SP1-p107p1 - complex
	p107p1 - complex
	SP1-p107 - complex
	p107 - complex
	cdk1p3-cycA - complex
	Wee1p1 - complex
	cdk1p3-cycB - complex)


(:init
	(possible Wee1)
	(= (available Wee1) 0)
	(possible SP1)
	(= (available SP1) 0)
	(possible Skp2)
	(= (available Skp2) 0)
	(possible RPA)
	(= (available RPA) 0)
	(possible pRb-E2F4p1-DP12)
	(= (available pRb-E2F4p1-DP12) 0)
	(possible pRb)
	(= (available pRb) 0)
	(possible Plk1)
	(= (available Plk1) 0)
	(possible p57)
	(= (available p57) 0)
	(possible p53p1)
	(= (available p53p1) 0)
	(possible p53)
	(= (available p53) 0)
	(possible p27)
	(= (available p27) 0)
	(possible Max)
	(= (available Max) 0)
	(possible m1433)
	(= (available m1433) 0)
	(possible Jun)
	(= (available Jun) 0)
	(possible HDAC1-pRbp1-E2F13p1-DP12)
	(= (available HDAC1-pRbp1-E2F13p1-DP12) 0)
	(possible HDAC1-pRbp1-E2F13-DP12)
	(= (available HDAC1-pRbp1-E2F13-DP12) 0)
	(possible HDAC1-p130-E2F4p1-DP12)
	(= (available HDAC1-p130-E2F4p1-DP12) 0)
	(possible HDAC1-p107-E2F4p1-DP12)
	(= (available HDAC1-p107-E2F4p1-DP12) 0)
	(possible HDAC1)
	(= (available HDAC1) 0)
	(possible gp19ARF)
	(= (available gp19ARF) 0)
	(possible gERCC1)
	(= (available gERCC1) 0)
	(possible gE-c)
	(= (available gE-c) 0)
	(possible gE2)
	(= (available gE2) 0)
	(possible E2F13p1-DP12p1)
	(= (available E2F13p1-DP12p1) 0)
	(possible E2F13p1-DP12)
	(= (available E2F13p1-DP12) 0)
	(possible E2F13-DP12p1)
	(= (available E2F13-DP12p1) 0)
	(possible E2F13-DP12)
	(= (available E2F13-DP12) 0)
	(possible E2F13)
	(= (available E2F13) 0)
	(possible DMP1)
	(= (available DMP1) 0)
	(possible cycH)
	(= (available cycH) 0)
	(possible cycB)
	(= (available cycB) 0)
	(possible C-TAK1)
	(= (available C-TAK1) 0)
	(possible cks1)
	(= (available cks1) 0)
	(possible Chk1)
	(= (available Chk1) 0)
	(possible cdk7)
	(= (available cdk7) 0)
	(possible cdk46p3-cycDp1)
	(= (available cdk46p3-cycDp1) 0)
	(possible cdk2p2-cycB)
	(= (available cdk2p2-cycB) 0)
	(possible cdk2p1)
	(= (available cdk2p1) 0)
	(possible cdk1p1p2)
	(= (available cdk1p1p2) 0)
	(possible cdc25C)
	(= (available cdc25C) 0)
	(possible c-Abl)
	(= (available c-Abl) 0)
	(possible APC)
	(= (available APC) 0)
	(possible AP2)
	(= (available AP2) 0)
	(= (available AP2-gE-c) 0)
	(= (available c-Abl-pRb) 0)
	(= (available c-Abl-pRbp1) 0)
	(= (available cdk1-cks1) 0)
	(= (available cdk1-Gadd45) 0)
	(= (available cdk1p1-cks1) 0)
	(= (available cdk1p1-Gadd45) 0)
	(= (available cdk1p1) 0)
	(= (available cdk1p1p2-cks1) 0)
	(= (available cdk1p1p2-Gadd45) 0)
	(= (available cdk1p1p2p3-cks1) 0)
	(= (available cdk1p1p2p3-Gadd45) 0)
	(= (available cdk1p1p2p3) 0)
	(= (available cdk1p1p3-cks1) 0)
	(= (available cdk1p1p3-Gadd45) 0)
	(= (available cdk1p1p3) 0)
	(= (available cdk1) 0)
	(= (available cdk1p2-cks1) 0)
	(= (available cdk1p2-Gadd45) 0)
	(= (available cdk1p2) 0)
	(= (available cdk1p2p3-cks1) 0)
	(= (available cdk1p1p2p3-cycA) 0)
	(= (available cdc25Cp1) 0)
	(= (available cdk1p1p2p3-cycB) 0)
	(= (available cdk1p2p3-Gadd45) 0)
	(= (available cdk1p2p3) 0)
	(= (available cdk1p3-cks1) 0)
	(= (available cdk1p1p3-cycA) 0)
	(= (available cdk1p2p3-cycA) 0)
	(= (available cdk1p1p3-cycB) 0)
	(= (available cdk1p2p3-cycB) 0)
	(= (available cdk1p3-Gadd45) 0)
	(= (available cdk1p3) 0)
	(= (available cdk2p1-cks1) 0)
	(= (available cdk2p1-cycA-E2F13) 0)
	(= (available cdk2p1p2-cks1) 0)
	(= (available cdk2p1p2-cycA-E2F13) 0)
	(= (available cdk2p1p2) 0)
	(= (available cdk2p1p2-cycB) 0)
	(= (available cdk7-cycH) 0)
	(= (available cdk7p1-cycH) 0)
	(= (available c-Myc-AP2) 0)
	(= (available c-Myc-Max) 0)
	(= (available APCp1) 0)
	(= (available DMP1-cycD) 0)
	(= (available DMP1-cycDp1) 0)
	(= (available DMP1-gp19ARF) 0)
	(= (available DMP1p1-cycD) 0)
	(= (available DMP1p1-cycDp1) 0)
	(= (available DMP1p1) 0)
	(= (available DMP1p1-gp19ARF) 0)
	(= (available E2F13-DP12-gE2) 0)
	(= (available E2F13p1-DP12-gE2) 0)
	(= (available HDAC1-p107-E2F4p1-DP12-gE2) 0)
	(= (available HDAC1-p130-E2F4p1-DP12-gE2) 0)
	(= (available HDAC1-pRb-E2F13-DP12-gE2) 0)
	(= (available HDAC1-pRb-E2F13-DP12) 0)
	(= (available HDAC1-pRb-E2F13-DP12p1) 0)
	(= (available HDAC1-pRb-E2F13p1-DP12-gE2) 0)
	(= (available HDAC1-pRb-E2F13p1-DP12) 0)
	(= (available HDAC1-pRb-E2F13p1-DP12p1) 0)
	(= (available HDAC1-pRb-E2F4p1-DP12) 0)
	(= (available HDAC1-pRbp1-E2F13-DP12-gE2) 0)
	(= (available HDAC1-pRbp1-E2F13p1-DP12-gE2) 0)
	(= (available Jun-c-Fos-gERCC1) 0)
	(= (available Jun-c-Fos) 0)
	(= (available m1433-cdc25Cp1p2) 0)
	(= (available cdc25Cp1p2) 0)
	(= (available m1433-cdc25Cp2) 0)
	(= (available cdc25Cp2) 0)
	(= (available Mdm2-E2F13-DP12) 0)
	(= (available Mdm2-E2F13-DP12p1) 0)
	(= (available Mdm2-E2F13p1-DP12) 0)
	(= (available Mdm2-E2F13p1-DP12p1) 0)
	(= (available Mdm2-pRb) 0)
	(= (available Mdm2-pRbp1) 0)
	(= (available cdk7p1) 0)
	(= (available p21-cdk2p1-cycA) 0)
	(= (available p21-cdk2p1-cycEp1) 0)
	(= (available p21-cdk2p1-cycE) 0)
	(= (available p21-cdk2p1p2-cycA) 0)
	(= (available p21-cdk2p1p2-cycEp1) 0)
	(= (available p21-cdk2p1p2-cycE) 0)
	(= (available p21-Gadd45) 0)
	(= (available p27-cdk2p1-cycA) 0)
	(= (available p27-cdk2p1-cycEp1) 0)
	(= (available p27-cdk2p1-cycE) 0)
	(= (available p27-cdk2p1p2-cycA) 0)
	(= (available p27-cdk2p1p2-cycEp1) 0)
	(= (available p27-cdk2p1p2-cycE) 0)
	(= (available Mdm2) 0)
	(= (available p57-cdk2p1-cycA) 0)
	(= (available p57-cdk2p1-cycEp1) 0)
	(= (available p57-cdk2p1-cycE) 0)
	(= (available p57-cdk2p1p2-cycA) 0)
	(= (available p57-cdk2p1p2-cycEp1) 0)
	(= (available p57-cdk2p1p2-cycE) 0)
	(= (available Gadd45) 0)
	(= (available cdk2p1-cycEp1) 0)
	(= (available cdk2p1-cycE) 0)
	(= (available cdk2p1p2-cycEp1) 0)
	(= (available cdk2p1p2-cycE) 0)
	(= (available p21) 0)
	(= (available pRb-AP2-gE-c) 0)
	(= (available pRb-AP2) 0)
	(= (available pRb-E2F13-DP12-gE2) 0)
	(= (available pRb-E2F13-DP12p1-gE2) 0)
	(= (available pRb-E2F13p1-DP12-gE2) 0)
	(= (available pRb-E2F13p1-DP12p1-gE2) 0)
	(= (available pRb-E2F4p1-DP12-gE2) 0)
	(= (available pRb-Jun-c-Fos-gERCC1) 0)
	(= (available pRb-Jun-c-Fos) 0)
	(= (available pRb-Jun) 0)
	(= (available pRbp1-AP2-gE-c) 0)
	(= (available pRbp1-AP2) 0)
	(= (available pRbp1-E2F13-DP12-gE2) 0)
	(= (available pRbp1-E2F13-DP12p1-gE2) 0)
	(= (available pRbp1-E2F13p1-DP12-gE2) 0)
	(= (available pRbp1-E2F13p1-DP12p1-gE2) 0)
	(= (available pRbp1-Jun-c-Fos-gERCC1) 0)
	(= (available pRbp1-Jun-c-Fos) 0)
	(= (available pRbp1-Jun) 0)
	(= (available pRbp1) 0)
	(= (available Ecadherin) 0)
	(= (available ERCC1) 0)
	(= (available c-Fos) 0)
	(= (available pRb-E2F13-DP12p1) 0)
	(= (available pRb-E2F13-DP12) 0)
	(= (available pRb-E2F13p1-DP12p1) 0)
	(= (available pRb-E2F13p1-DP12) 0)
	(= (available pRbp1-E2F13-DP12p1) 0)
	(= (available pRbp1-E2F13-DP12) 0)
	(= (available pRbp1-E2F13p1-DP12p1) 0)
	(= (available pRbp1-E2F13p1-DP12) 0)
	(= (available RPA-cycA) 0)
	(= (available Skp2-cdk2p1-cycA) 0)
	(= (available Skp2-cdk2p1p2-cycA) 0)
	(= (available cdk2p1-cycA) 0)
	(= (available cdk2p1p2-cycA) 0)
	(= (available SP1-E2F13) 0)
	(= (available c-Myc) 0)
	(= (available cycA) 0)
	(= (available cycD) 0)
	(= (available cycDp1) 0)
	(= (available cycE) 0)
	(= (available cycEp1) 0)
	(= (available p19ARF) 0)
	(= (available pol) 0)
	(= (available SP1-p107p1) 0)
	(= (available p107p1) 0)
	(= (available SP1-p107) 0)
	(= (available p107) 0)
	(= (available cdk1p3-cycA) 0)
	(= (available Wee1p1) 0)
	(= (available cdk1p3-cycB) 0)
	(association-reaction AP2 gE-c AP2-gE-c)
	(= (need-for-association AP2 gE-c AP2-gE-c) 4)
	(= (need-for-association gE-c AP2 AP2-gE-c) 1)
	(= (prod-by-association AP2 gE-c AP2-gE-c) 1)
	(synthesis-reaction AP2-gE-c Ecadherin) 
	(= (need-for-synthesis AP2-gE-c Ecadherin) 2)
	(= (prod-by-synthesis AP2-gE-c Ecadherin) 1)
	(catalyzed-association-reaction APC Plk1 APCp1)
	(= (need-for-catalyzed-association APC Plk1 APCp1) 3)
	(= (need-for-catalyzed-association Plk1 APC APCp1) 1)
	(= (prod-by-catalyzed-association APC Plk1 APCp1) 2)
	(association-reaction c-Abl pRb c-Abl-pRb)
	(= (need-for-association c-Abl pRb c-Abl-pRb) 1)
	(= (need-for-association pRb c-Abl c-Abl-pRb) 2)
	(= (prod-by-association c-Abl pRb c-Abl-pRb) 3)
	(association-reaction c-Abl pRbp1 c-Abl-pRbp1)
	(= (need-for-association c-Abl pRbp1 c-Abl-pRbp1) 2)
	(= (need-for-association pRbp1 c-Abl c-Abl-pRbp1) 4)
	(= (prod-by-association c-Abl pRbp1 c-Abl-pRbp1) 1)
	(catalyzed-association-reaction cdc25C cdk1p3-cycA cdc25Cp1)
	(= (need-for-catalyzed-association cdc25C cdk1p3-cycA cdc25Cp1) 3)
	(= (need-for-catalyzed-association cdk1p3-cycA cdc25C cdc25Cp1) 3)
	(= (prod-by-catalyzed-association cdc25C cdk1p3-cycA cdc25Cp1) 4)
	(catalyzed-association-reaction cdc25C cdk1p3-cycB cdc25Cp1)
	(= (need-for-catalyzed-association cdc25C cdk1p3-cycB cdc25Cp1) 1)
	(= (need-for-catalyzed-association cdk1p3-cycB cdc25C cdc25Cp1) 1)
	(= (prod-by-catalyzed-association cdc25C cdk1p3-cycB cdc25Cp1) 1)
	(catalyzed-association-reaction cdc25C Chk1 cdc25Cp2)
	(= (need-for-catalyzed-association cdc25C Chk1 cdc25Cp2) 4)
	(= (need-for-catalyzed-association Chk1 cdc25C cdc25Cp2) 2)
	(= (prod-by-catalyzed-association cdc25C Chk1 cdc25Cp2) 3)
	(catalyzed-association-reaction cdc25C C-TAK1 cdc25Cp2)
	(= (need-for-catalyzed-association cdc25C C-TAK1 cdc25Cp2) 2)
	(= (need-for-catalyzed-association C-TAK1 cdc25C cdc25Cp2) 3)
	(= (prod-by-catalyzed-association cdc25C C-TAK1 cdc25Cp2) 1)
	(catalyzed-association-reaction cdc25Cp1 Chk1 cdc25Cp1p2)
	(= (need-for-catalyzed-association cdc25Cp1 Chk1 cdc25Cp1p2) 2)
	(= (need-for-catalyzed-association Chk1 cdc25Cp1 cdc25Cp1p2) 2)
	(= (prod-by-catalyzed-association cdc25Cp1 Chk1 cdc25Cp1p2) 2)
	(catalyzed-association-reaction cdc25Cp1 C-TAK1 cdc25Cp1p2)
	(= (need-for-catalyzed-association cdc25Cp1 C-TAK1 cdc25Cp1p2) 3)
	(= (need-for-catalyzed-association C-TAK1 cdc25Cp1 cdc25Cp1p2) 4)
	(= (prod-by-catalyzed-association cdc25Cp1 C-TAK1 cdc25Cp1p2) 1)
	(catalyzed-association-reaction cdc25Cp2 cdk1p3-cycA cdc25Cp1p2)
	(= (need-for-catalyzed-association cdc25Cp2 cdk1p3-cycA cdc25Cp1p2) 3)
	(= (need-for-catalyzed-association cdk1p3-cycA cdc25Cp2 cdc25Cp1p2) 4)
	(= (prod-by-catalyzed-association cdc25Cp2 cdk1p3-cycA cdc25Cp1p2) 2)
	(catalyzed-association-reaction cdc25Cp2 cdk1p3-cycB cdc25Cp1p2)
	(= (need-for-catalyzed-association cdc25Cp2 cdk1p3-cycB cdc25Cp1p2) 3)
	(= (need-for-catalyzed-association cdk1p3-cycB cdc25Cp2 cdc25Cp1p2) 2)
	(= (prod-by-catalyzed-association cdc25Cp2 cdk1p3-cycB cdc25Cp1p2) 3)
	(catalyzed-association-reaction cdc25Cp2 Plk1 cdc25Cp1p2)
	(= (need-for-catalyzed-association cdc25Cp2 Plk1 cdc25Cp1p2) 4)
	(= (need-for-catalyzed-association Plk1 cdc25Cp2 cdc25Cp1p2) 2)
	(= (prod-by-catalyzed-association cdc25Cp2 Plk1 cdc25Cp1p2) 4)
	(catalyzed-association-reaction cdc25C Plk1 cdc25Cp1)
	(= (need-for-catalyzed-association cdc25C Plk1 cdc25Cp1) 3)
	(= (need-for-catalyzed-association Plk1 cdc25C cdc25Cp1) 4)
	(= (prod-by-catalyzed-association cdc25C Plk1 cdc25Cp1) 3)
	(catalyzed-association-reaction cdk1 cdk7-cycH cdk1p3)
	(= (need-for-catalyzed-association cdk1 cdk7-cycH cdk1p3) 3)
	(= (need-for-catalyzed-association cdk7-cycH cdk1 cdk1p3) 2)
	(= (prod-by-catalyzed-association cdk1 cdk7-cycH cdk1p3) 1)
	(association-reaction cdk1 cks1 cdk1-cks1)
	(= (need-for-association cdk1 cks1 cdk1-cks1) 2)
	(= (need-for-association cks1 cdk1 cdk1-cks1) 2)
	(= (prod-by-association cdk1 cks1 cdk1-cks1) 2)
	(association-reaction cdk1 Gadd45 cdk1-Gadd45)
	(= (need-for-association cdk1 Gadd45 cdk1-Gadd45) 3)
	(= (need-for-association Gadd45 cdk1 cdk1-Gadd45) 1)
	(= (prod-by-association cdk1 Gadd45 cdk1-Gadd45) 3)
	(catalyzed-association-reaction cdk1p1 cdc25Cp1 cdk1)
	(= (need-for-catalyzed-association cdk1p1 cdc25Cp1 cdk1) 1)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1 cdk1) 3)
	(= (prod-by-catalyzed-association cdk1p1 cdc25Cp1 cdk1) 2)
	(catalyzed-association-reaction cdk1p1 cdc25Cp1p2 cdk1)
	(= (need-for-catalyzed-association cdk1p1 cdc25Cp1p2 cdk1) 1)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1 cdk1) 4)
	(= (prod-by-catalyzed-association cdk1p1 cdc25Cp1p2 cdk1) 3)
	(catalyzed-association-reaction cdk1p1 cdk7-cycH cdk1p1p3)
	(= (need-for-catalyzed-association cdk1p1 cdk7-cycH cdk1p1p3) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk1p1 cdk1p1p3) 2)
	(= (prod-by-catalyzed-association cdk1p1 cdk7-cycH cdk1p1p3) 3)
	(association-reaction cdk1p1 cks1 cdk1p1-cks1)
	(= (need-for-association cdk1p1 cks1 cdk1p1-cks1) 3)
	(= (need-for-association cks1 cdk1p1 cdk1p1-cks1) 1)
	(= (prod-by-association cdk1p1 cks1 cdk1p1-cks1) 2)
	(association-reaction cdk1p1 Gadd45 cdk1p1-Gadd45)
	(= (need-for-association cdk1p1 Gadd45 cdk1p1-Gadd45) 4)
	(= (need-for-association Gadd45 cdk1p1 cdk1p1-Gadd45) 3)
	(= (prod-by-association cdk1p1 Gadd45 cdk1p1-Gadd45) 4)
	(catalyzed-association-reaction cdk1p1p2 cdc25Cp1 cdk1p1)
	(= (need-for-catalyzed-association cdk1p1p2 cdc25Cp1 cdk1p1) 2)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2 cdk1p1) 3)
	(= (prod-by-catalyzed-association cdk1p1p2 cdc25Cp1 cdk1p1) 1)
	(catalyzed-association-reaction cdk1p1p2 cdc25Cp1 cdk1p2)
	(= (need-for-catalyzed-association cdk1p1p2 cdc25Cp1 cdk1p2) 1)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2 cdk1p2) 1)
	(= (prod-by-catalyzed-association cdk1p1p2 cdc25Cp1 cdk1p2) 4)
	(catalyzed-association-reaction cdk1p1p2 cdc25Cp1p2 cdk1p1)
	(= (need-for-catalyzed-association cdk1p1p2 cdc25Cp1p2 cdk1p1) 4)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2 cdk1p1) 3)
	(= (prod-by-catalyzed-association cdk1p1p2 cdc25Cp1p2 cdk1p1) 1)
	(catalyzed-association-reaction cdk1p1p2 cdc25Cp1p2 cdk1p2)
	(= (need-for-catalyzed-association cdk1p1p2 cdc25Cp1p2 cdk1p2) 4)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2 cdk1p2) 4)
	(= (prod-by-catalyzed-association cdk1p1p2 cdc25Cp1p2 cdk1p2) 2)
	(catalyzed-association-reaction cdk1p1p2 cdk7-cycH cdk1p1p2p3)
	(= (need-for-catalyzed-association cdk1p1p2 cdk7-cycH cdk1p1p2p3) 1)
	(= (need-for-catalyzed-association cdk7-cycH cdk1p1p2 cdk1p1p2p3) 2)
	(= (prod-by-catalyzed-association cdk1p1p2 cdk7-cycH cdk1p1p2p3) 3)
	(association-reaction cdk1p1p2 cks1 cdk1p1p2-cks1)
	(= (need-for-association cdk1p1p2 cks1 cdk1p1p2-cks1) 4)
	(= (need-for-association cks1 cdk1p1p2 cdk1p1p2-cks1) 3)
	(= (prod-by-association cdk1p1p2 cks1 cdk1p1p2-cks1) 1)
	(association-reaction cdk1p1p2 Gadd45 cdk1p1p2-Gadd45)
	(= (need-for-association cdk1p1p2 Gadd45 cdk1p1p2-Gadd45) 1)
	(= (need-for-association Gadd45 cdk1p1p2 cdk1p1p2-Gadd45) 3)
	(= (prod-by-association cdk1p1p2 Gadd45 cdk1p1p2-Gadd45) 4)
	(catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1 cdk1p1p3)
	(= (need-for-catalyzed-association cdk1p1p2p3 cdc25Cp1 cdk1p1p3) 3)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3 cdk1p1p3) 1)
	(= (prod-by-catalyzed-association cdk1p1p2p3 cdc25Cp1 cdk1p1p3) 2)
	(catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1 cdk1p2p3)
	(= (need-for-catalyzed-association cdk1p1p2p3 cdc25Cp1 cdk1p2p3) 1)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3 cdk1p2p3) 3)
	(= (prod-by-catalyzed-association cdk1p1p2p3 cdc25Cp1 cdk1p2p3) 2)
	(catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1p2 cdk1p1p3)
	(= (need-for-catalyzed-association cdk1p1p2p3 cdc25Cp1p2 cdk1p1p3) 3)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3 cdk1p1p3) 2)
	(= (prod-by-catalyzed-association cdk1p1p2p3 cdc25Cp1p2 cdk1p1p3) 4)
	(catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1p2 cdk1p2p3)
	(= (need-for-catalyzed-association cdk1p1p2p3 cdc25Cp1p2 cdk1p2p3) 2)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3 cdk1p2p3) 4)
	(= (prod-by-catalyzed-association cdk1p1p2p3 cdc25Cp1p2 cdk1p2p3) 2)
	(association-reaction cdk1p1p2p3 cks1 cdk1p1p2p3-cks1)
	(= (need-for-association cdk1p1p2p3 cks1 cdk1p1p2p3-cks1) 2)
	(= (need-for-association cks1 cdk1p1p2p3 cdk1p1p2p3-cks1) 4)
	(= (prod-by-association cdk1p1p2p3 cks1 cdk1p1p2p3-cks1) 2)
	(catalyzed-association-reaction cdk1p1p2p3-cycA cdc25Cp1 cdk1p1p3-cycA)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycA cdc25Cp1 cdk1p1p3-cycA) 2)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3-cycA cdk1p1p3-cycA) 3)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycA cdc25Cp1 cdk1p1p3-cycA) 4)
	(catalyzed-association-reaction cdk1p1p2p3-cycA cdc25Cp1 cdk1p2p3-cycA)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycA cdc25Cp1 cdk1p2p3-cycA) 2)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3-cycA cdk1p2p3-cycA) 3)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycA cdc25Cp1 cdk1p2p3-cycA) 4)
	(catalyzed-association-reaction cdk1p1p2p3-cycA cdc25Cp1p2 cdk1p1p3-cycA)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycA cdc25Cp1p2 cdk1p1p3-cycA) 4)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3-cycA cdk1p1p3-cycA) 3)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycA cdc25Cp1p2 cdk1p1p3-cycA) 1)
	(catalyzed-association-reaction cdk1p1p2p3-cycA cdc25Cp1p2 cdk1p2p3-cycA)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycA cdc25Cp1p2 cdk1p2p3-cycA) 2)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3-cycA cdk1p2p3-cycA) 2)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycA cdc25Cp1p2 cdk1p2p3-cycA) 3)
	(association-reaction cdk1p1p2p3 cycA cdk1p1p2p3-cycA)
	(= (need-for-association cdk1p1p2p3 cycA cdk1p1p2p3-cycA) 2)
	(= (need-for-association cycA cdk1p1p2p3 cdk1p1p2p3-cycA) 2)
	(= (prod-by-association cdk1p1p2p3 cycA cdk1p1p2p3-cycA) 2)
	(catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1 cdk1p1p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1 cdk1p1p3-cycB) 1)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3-cycB cdk1p1p3-cycB) 1)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1 cdk1p1p3-cycB) 2)
	(catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1 cdk1p2p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1 cdk1p2p3-cycB) 2)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3-cycB cdk1p2p3-cycB) 1)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1 cdk1p2p3-cycB) 4)
	(catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p1p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p1p3-cycB) 3)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3-cycB cdk1p1p3-cycB) 3)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p1p3-cycB) 1)
	(catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p2p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p2p3-cycB) 3)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3-cycB cdk1p2p3-cycB) 4)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p2p3-cycB) 4)
	(association-reaction cdk1p1p2p3 cycB cdk1p1p2p3-cycB)
	(= (need-for-association cdk1p1p2p3 cycB cdk1p1p2p3-cycB) 4)
	(= (need-for-association cycB cdk1p1p2p3 cdk1p1p2p3-cycB) 2)
	(= (prod-by-association cdk1p1p2p3 cycB cdk1p1p2p3-cycB) 4)
	(association-reaction cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45)
	(= (need-for-association cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45) 2)
	(= (need-for-association Gadd45 cdk1p1p2p3 cdk1p1p2p3-Gadd45) 3)
	(= (prod-by-association cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45) 2)
	(catalyzed-association-reaction cdk1p1p3 cdc25Cp1 cdk1p3)
	(= (need-for-catalyzed-association cdk1p1p3 cdc25Cp1 cdk1p3) 1)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p3 cdk1p3) 4)
	(= (prod-by-catalyzed-association cdk1p1p3 cdc25Cp1 cdk1p3) 4)
	(catalyzed-association-reaction cdk1p1p3 cdc25Cp1p2 cdk1p3)
	(= (need-for-catalyzed-association cdk1p1p3 cdc25Cp1p2 cdk1p3) 4)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p3 cdk1p3) 3)
	(= (prod-by-catalyzed-association cdk1p1p3 cdc25Cp1p2 cdk1p3) 3)
	(association-reaction cdk1p1p3 cks1 cdk1p1p3-cks1)
	(= (need-for-association cdk1p1p3 cks1 cdk1p1p3-cks1) 1)
	(= (need-for-association cks1 cdk1p1p3 cdk1p1p3-cks1) 4)
	(= (prod-by-association cdk1p1p3 cks1 cdk1p1p3-cks1) 4)
	(catalyzed-association-reaction cdk1p1p3-cycA cdc25Cp1 cdk1p3-cycA)
	(= (need-for-catalyzed-association cdk1p1p3-cycA cdc25Cp1 cdk1p3-cycA) 3)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p3-cycA cdk1p3-cycA) 1)
	(= (prod-by-catalyzed-association cdk1p1p3-cycA cdc25Cp1 cdk1p3-cycA) 2)
	(catalyzed-association-reaction cdk1p1p3-cycA cdc25Cp1p2 cdk1p3-cycA)
	(= (need-for-catalyzed-association cdk1p1p3-cycA cdc25Cp1p2 cdk1p3-cycA) 4)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p3-cycA cdk1p3-cycA) 2)
	(= (prod-by-catalyzed-association cdk1p1p3-cycA cdc25Cp1p2 cdk1p3-cycA) 2)
	(association-reaction cdk1p1p3 cycA cdk1p1p3-cycA)
	(= (need-for-association cdk1p1p3 cycA cdk1p1p3-cycA) 1)
	(= (need-for-association cycA cdk1p1p3 cdk1p1p3-cycA) 3)
	(= (prod-by-association cdk1p1p3 cycA cdk1p1p3-cycA) 2)
	(catalyzed-association-reaction cdk1p1p3-cycA Wee1 cdk1p1p2p3-cycA)
	(= (need-for-catalyzed-association cdk1p1p3-cycA Wee1 cdk1p1p2p3-cycA) 4)
	(= (need-for-catalyzed-association Wee1 cdk1p1p3-cycA cdk1p1p2p3-cycA) 2)
	(= (prod-by-catalyzed-association cdk1p1p3-cycA Wee1 cdk1p1p2p3-cycA) 1)
	(catalyzed-association-reaction cdk1p1p3-cycB cdc25Cp1 cdk1p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p3-cycB cdc25Cp1 cdk1p3-cycB) 1)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p3-cycB cdk1p3-cycB) 4)
	(= (prod-by-catalyzed-association cdk1p1p3-cycB cdc25Cp1 cdk1p3-cycB) 4)
	(catalyzed-association-reaction cdk1p1p3-cycB cdc25Cp1p2 cdk1p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p3-cycB cdc25Cp1p2 cdk1p3-cycB) 4)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p3-cycB cdk1p3-cycB) 3)
	(= (prod-by-catalyzed-association cdk1p1p3-cycB cdc25Cp1p2 cdk1p3-cycB) 1)
	(association-reaction cdk1p1p3 cycB cdk1p1p3-cycB)
	(= (need-for-association cdk1p1p3 cycB cdk1p1p3-cycB) 3)
	(= (need-for-association cycB cdk1p1p3 cdk1p1p3-cycB) 4)
	(= (prod-by-association cdk1p1p3 cycB cdk1p1p3-cycB) 3)
	(catalyzed-association-reaction cdk1p1p3-cycB Wee1 cdk1p1p2p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p3-cycB Wee1 cdk1p1p2p3-cycB) 1)
	(= (need-for-catalyzed-association Wee1 cdk1p1p3-cycB cdk1p1p2p3-cycB) 1)
	(= (prod-by-catalyzed-association cdk1p1p3-cycB Wee1 cdk1p1p2p3-cycB) 3)
	(association-reaction cdk1p1p3 Gadd45 cdk1p1p3-Gadd45)
	(= (need-for-association cdk1p1p3 Gadd45 cdk1p1p3-Gadd45) 4)
	(= (need-for-association Gadd45 cdk1p1p3 cdk1p1p3-Gadd45) 4)
	(= (prod-by-association cdk1p1p3 Gadd45 cdk1p1p3-Gadd45) 1)
	(catalyzed-association-reaction cdk1p2 cdc25Cp1 cdk1)
	(= (need-for-catalyzed-association cdk1p2 cdc25Cp1 cdk1) 2)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p2 cdk1) 4)
	(= (prod-by-catalyzed-association cdk1p2 cdc25Cp1 cdk1) 1)
	(catalyzed-association-reaction cdk1p2 cdc25Cp1p2 cdk1)
	(= (need-for-catalyzed-association cdk1p2 cdc25Cp1p2 cdk1) 2)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p2 cdk1) 3)
	(= (prod-by-catalyzed-association cdk1p2 cdc25Cp1p2 cdk1) 1)
	(catalyzed-association-reaction cdk1p2 cdk7-cycH cdk1p2p3)
	(= (need-for-catalyzed-association cdk1p2 cdk7-cycH cdk1p2p3) 3)
	(= (need-for-catalyzed-association cdk7-cycH cdk1p2 cdk1p2p3) 2)
	(= (prod-by-catalyzed-association cdk1p2 cdk7-cycH cdk1p2p3) 2)
	(association-reaction cdk1p2 cks1 cdk1p2-cks1)
	(= (need-for-association cdk1p2 cks1 cdk1p2-cks1) 4)
	(= (need-for-association cks1 cdk1p2 cdk1p2-cks1) 3)
	(= (prod-by-association cdk1p2 cks1 cdk1p2-cks1) 1)
	(association-reaction cdk1p2 Gadd45 cdk1p2-Gadd45)
	(= (need-for-association cdk1p2 Gadd45 cdk1p2-Gadd45) 1)
	(= (need-for-association Gadd45 cdk1p2 cdk1p2-Gadd45) 2)
	(= (prod-by-association cdk1p2 Gadd45 cdk1p2-Gadd45) 2)
	(catalyzed-association-reaction cdk1p2p3 cdc25Cp1 cdk1p3)
	(= (need-for-catalyzed-association cdk1p2p3 cdc25Cp1 cdk1p3) 1)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p2p3 cdk1p3) 2)
	(= (prod-by-catalyzed-association cdk1p2p3 cdc25Cp1 cdk1p3) 1)
	(catalyzed-association-reaction cdk1p2p3 cdc25Cp1p2 cdk1p3)
	(= (need-for-catalyzed-association cdk1p2p3 cdc25Cp1p2 cdk1p3) 1)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p2p3 cdk1p3) 2)
	(= (prod-by-catalyzed-association cdk1p2p3 cdc25Cp1p2 cdk1p3) 3)
	(association-reaction cdk1p2p3 cks1 cdk1p2p3-cks1)
	(= (need-for-association cdk1p2p3 cks1 cdk1p2p3-cks1) 1)
	(= (need-for-association cks1 cdk1p2p3 cdk1p2p3-cks1) 4)
	(= (prod-by-association cdk1p2p3 cks1 cdk1p2p3-cks1) 3)
	(catalyzed-association-reaction cdk1p2p3-cycA cdc25Cp1 cdk1p3-cycA)
	(= (need-for-catalyzed-association cdk1p2p3-cycA cdc25Cp1 cdk1p3-cycA) 4)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p2p3-cycA cdk1p3-cycA) 4)
	(= (prod-by-catalyzed-association cdk1p2p3-cycA cdc25Cp1 cdk1p3-cycA) 3)
	(catalyzed-association-reaction cdk1p2p3-cycA cdc25Cp1p2 cdk1p3-cycA)
	(= (need-for-catalyzed-association cdk1p2p3-cycA cdc25Cp1p2 cdk1p3-cycA) 2)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p2p3-cycA cdk1p3-cycA) 4)
	(= (prod-by-catalyzed-association cdk1p2p3-cycA cdc25Cp1p2 cdk1p3-cycA) 2)
	(association-reaction cdk1p2p3 cycA cdk1p2p3-cycA)
	(= (need-for-association cdk1p2p3 cycA cdk1p2p3-cycA) 2)
	(= (need-for-association cycA cdk1p2p3 cdk1p2p3-cycA) 1)
	(= (prod-by-association cdk1p2p3 cycA cdk1p2p3-cycA) 2)
	(catalyzed-association-reaction cdk1p2p3-cycB cdc25Cp1 cdk1p3-cycB)
	(= (need-for-catalyzed-association cdk1p2p3-cycB cdc25Cp1 cdk1p3-cycB) 2)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p2p3-cycB cdk1p3-cycB) 2)
	(= (prod-by-catalyzed-association cdk1p2p3-cycB cdc25Cp1 cdk1p3-cycB) 4)
	(catalyzed-association-reaction cdk1p2p3-cycB cdc25Cp1p2 cdk1p3-cycB)
	(= (need-for-catalyzed-association cdk1p2p3-cycB cdc25Cp1p2 cdk1p3-cycB) 3)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p2p3-cycB cdk1p3-cycB) 4)
	(= (prod-by-catalyzed-association cdk1p2p3-cycB cdc25Cp1p2 cdk1p3-cycB) 1)
	(association-reaction cdk1p2p3 cycB cdk1p2p3-cycB)
	(= (need-for-association cdk1p2p3 cycB cdk1p2p3-cycB) 4)
	(= (need-for-association cycB cdk1p2p3 cdk1p2p3-cycB) 3)
	(= (prod-by-association cdk1p2p3 cycB cdk1p2p3-cycB) 3)
	(association-reaction cdk1p2p3 Gadd45 cdk1p2p3-Gadd45)
	(= (need-for-association cdk1p2p3 Gadd45 cdk1p2p3-Gadd45) 4)
	(= (need-for-association Gadd45 cdk1p2p3 cdk1p2p3-Gadd45) 4)
	(= (prod-by-association cdk1p2p3 Gadd45 cdk1p2p3-Gadd45) 1)
	(association-reaction cdk1p3 cks1 cdk1p3-cks1)
	(= (need-for-association cdk1p3 cks1 cdk1p3-cks1) 1)
	(= (need-for-association cks1 cdk1p3 cdk1p3-cks1) 4)
	(= (prod-by-association cdk1p3 cks1 cdk1p3-cks1) 2)
	(association-reaction cdk1p3 cycA cdk1p3-cycA)
	(= (need-for-association cdk1p3 cycA cdk1p3-cycA) 1)
	(= (need-for-association cycA cdk1p3 cdk1p3-cycA) 4)
	(= (prod-by-association cdk1p3 cycA cdk1p3-cycA) 3)
	(catalyzed-association-reaction cdk1p3-cycA Wee1 cdk1p2p3-cycA)
	(= (need-for-catalyzed-association cdk1p3-cycA Wee1 cdk1p2p3-cycA) 4)
	(= (need-for-catalyzed-association Wee1 cdk1p3-cycA cdk1p2p3-cycA) 1)
	(= (prod-by-catalyzed-association cdk1p3-cycA Wee1 cdk1p2p3-cycA) 3)
	(association-reaction cdk1p3 cycB cdk1p3-cycB)
	(= (need-for-association cdk1p3 cycB cdk1p3-cycB) 2)
	(= (need-for-association cycB cdk1p3 cdk1p3-cycB) 4)
	(= (prod-by-association cdk1p3 cycB cdk1p3-cycB) 2)
	(catalyzed-association-reaction cdk1p3-cycB Wee1 cdk1p2p3-cycB)
	(= (need-for-catalyzed-association cdk1p3-cycB Wee1 cdk1p2p3-cycB) 4)
	(= (need-for-catalyzed-association Wee1 cdk1p3-cycB cdk1p2p3-cycB) 1)
	(= (prod-by-catalyzed-association cdk1p3-cycB Wee1 cdk1p2p3-cycB) 1)
	(association-reaction cdk1p3 Gadd45 cdk1p3-Gadd45)
	(= (need-for-association cdk1p3 Gadd45 cdk1p3-Gadd45) 1)
	(= (need-for-association Gadd45 cdk1p3 cdk1p3-Gadd45) 2)
	(= (prod-by-association cdk1p3 Gadd45 cdk1p3-Gadd45) 2)
	(catalyzed-association-reaction cdk2p1 cdk7-cycH cdk2p1p2)
	(= (need-for-catalyzed-association cdk2p1 cdk7-cycH cdk2p1p2) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk2p1 cdk2p1p2) 4)
	(= (prod-by-catalyzed-association cdk2p1 cdk7-cycH cdk2p1p2) 3)
	(association-reaction cdk2p1 cks1 cdk2p1-cks1)
	(= (need-for-association cdk2p1 cks1 cdk2p1-cks1) 1)
	(= (need-for-association cks1 cdk2p1 cdk2p1-cks1) 2)
	(= (prod-by-association cdk2p1 cks1 cdk2p1-cks1) 3)
	(association-reaction cdk2p1 cycA cdk2p1-cycA)
	(= (need-for-association cdk2p1 cycA cdk2p1-cycA) 2)
	(= (need-for-association cycA cdk2p1 cdk2p1-cycA) 1)
	(= (prod-by-association cdk2p1 cycA cdk2p1-cycA) 1)
	(catalyzed-association-reaction cdk2p1-cycA cdk7-cycH cdk2p1p2-cycA)
	(= (need-for-catalyzed-association cdk2p1-cycA cdk7-cycH cdk2p1p2-cycA) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk2p1-cycA cdk2p1p2-cycA) 1)
	(= (prod-by-catalyzed-association cdk2p1-cycA cdk7-cycH cdk2p1p2-cycA) 4)
	(association-reaction cdk2p1-cycA E2F13 cdk2p1-cycA-E2F13)
	(= (need-for-association cdk2p1-cycA E2F13 cdk2p1-cycA-E2F13) 4)
	(= (need-for-association E2F13 cdk2p1-cycA cdk2p1-cycA-E2F13) 1)
	(= (prod-by-association cdk2p1-cycA E2F13 cdk2p1-cycA-E2F13) 4)
	(association-reaction cdk2p1 cycE cdk2p1-cycE)
	(= (need-for-association cdk2p1 cycE cdk2p1-cycE) 2)
	(= (need-for-association cycE cdk2p1 cdk2p1-cycE) 2)
	(= (prod-by-association cdk2p1 cycE cdk2p1-cycE) 3)
	(catalyzed-association-reaction cdk2p1-cycE cdk7-cycH cdk2p1p2-cycE)
	(= (need-for-catalyzed-association cdk2p1-cycE cdk7-cycH cdk2p1p2-cycE) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk2p1-cycE cdk2p1p2-cycE) 1)
	(= (prod-by-catalyzed-association cdk2p1-cycE cdk7-cycH cdk2p1p2-cycE) 3)
	(association-reaction cdk2p1 cycEp1 cdk2p1-cycEp1)
	(= (need-for-association cdk2p1 cycEp1 cdk2p1-cycEp1) 2)
	(= (need-for-association cycEp1 cdk2p1 cdk2p1-cycEp1) 2)
	(= (prod-by-association cdk2p1 cycEp1 cdk2p1-cycEp1) 2)
	(catalyzed-association-reaction cdk2p1-cycEp1 cdk7-cycH cdk2p1p2-cycEp1)
	(= (need-for-catalyzed-association cdk2p1-cycEp1 cdk7-cycH cdk2p1p2-cycEp1) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk2p1-cycEp1 cdk2p1p2-cycEp1) 1)
	(= (prod-by-catalyzed-association cdk2p1-cycEp1 cdk7-cycH cdk2p1p2-cycEp1) 2)
	(association-reaction cdk2p1p2 cks1 cdk2p1p2-cks1)
	(= (need-for-association cdk2p1p2 cks1 cdk2p1p2-cks1) 4)
	(= (need-for-association cks1 cdk2p1p2 cdk2p1p2-cks1) 1)
	(= (prod-by-association cdk2p1p2 cks1 cdk2p1p2-cks1) 4)
	(association-reaction cdk2p1p2 cycA cdk2p1p2-cycA)
	(= (need-for-association cdk2p1p2 cycA cdk2p1p2-cycA) 1)
	(= (need-for-association cycA cdk2p1p2 cdk2p1p2-cycA) 3)
	(= (prod-by-association cdk2p1p2 cycA cdk2p1p2-cycA) 3)
	(association-reaction cdk2p1p2-cycA E2F13 cdk2p1p2-cycA-E2F13)
	(= (need-for-association cdk2p1p2-cycA E2F13 cdk2p1p2-cycA-E2F13) 4)
	(= (need-for-association E2F13 cdk2p1p2-cycA cdk2p1p2-cycA-E2F13) 3)
	(= (prod-by-association cdk2p1p2-cycA E2F13 cdk2p1p2-cycA-E2F13) 4)
	(association-reaction cdk2p1p2 cycE cdk2p1p2-cycE)
	(= (need-for-association cdk2p1p2 cycE cdk2p1p2-cycE) 2)
	(= (need-for-association cycE cdk2p1p2 cdk2p1p2-cycE) 4)
	(= (prod-by-association cdk2p1p2 cycE cdk2p1p2-cycE) 4)
	(association-reaction cdk2p1p2 cycEp1 cdk2p1p2-cycEp1)
	(= (need-for-association cdk2p1p2 cycEp1 cdk2p1p2-cycEp1) 2)
	(= (need-for-association cycEp1 cdk2p1p2 cdk2p1p2-cycEp1) 4)
	(= (prod-by-association cdk2p1p2 cycEp1 cdk2p1p2-cycEp1) 4)
	(catalyzed-association-reaction cdk2p2-cycB Wee1 cdk2p1p2-cycB)
	(= (need-for-catalyzed-association cdk2p2-cycB Wee1 cdk2p1p2-cycB) 2)
	(= (need-for-catalyzed-association Wee1 cdk2p2-cycB cdk2p1p2-cycB) 3)
	(= (prod-by-catalyzed-association cdk2p2-cycB Wee1 cdk2p1p2-cycB) 1)
	(catalyzed-association-reaction cdk7 cdk7-cycH cdk7p1)
	(= (need-for-catalyzed-association cdk7 cdk7-cycH cdk7p1) 1)
	(= (need-for-catalyzed-association cdk7-cycH cdk7 cdk7p1) 4)
	(= (prod-by-catalyzed-association cdk7 cdk7-cycH cdk7p1) 2)
	(association-reaction cdk7 cycH cdk7-cycH)
	(= (need-for-association cdk7 cycH cdk7-cycH) 3)
	(= (need-for-association cycH cdk7 cdk7-cycH) 4)
	(= (prod-by-association cdk7 cycH cdk7-cycH) 2)
	(catalyzed-association-reaction cdk7-cycH cdk7-cycH cdk7p1-cycH)
	(= (need-for-catalyzed-association cdk7-cycH cdk7-cycH cdk7p1-cycH) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk7-cycH cdk7p1-cycH) 1)
	(= (prod-by-catalyzed-association cdk7-cycH cdk7-cycH cdk7p1-cycH) 3)
	(association-reaction cdk7p1 cycH cdk7p1-cycH)
	(= (need-for-association cdk7p1 cycH cdk7p1-cycH) 3)
	(= (need-for-association cycH cdk7p1 cdk7p1-cycH) 4)
	(= (prod-by-association cdk7p1 cycH cdk7p1-cycH) 3)
	(association-reaction c-Myc AP2 c-Myc-AP2)
	(= (need-for-association c-Myc AP2 c-Myc-AP2) 1)
	(= (need-for-association AP2 c-Myc c-Myc-AP2) 4)
	(= (prod-by-association c-Myc AP2 c-Myc-AP2) 3)
	(association-reaction c-Myc Max c-Myc-Max)
	(= (need-for-association c-Myc Max c-Myc-Max) 4)
	(= (need-for-association Max c-Myc c-Myc-Max) 4)
	(= (prod-by-association c-Myc Max c-Myc-Max) 1)
	(catalyzed-association-reaction cycB APCp1 APCp1)
	(= (need-for-catalyzed-association cycB APCp1 APCp1) 2)
	(= (need-for-catalyzed-association APCp1 cycB APCp1) 3)
	(= (prod-by-catalyzed-association cycB APCp1 APCp1) 4)
	(catalyzed-association-reaction DMP1 cdk46p3-cycDp1 DMP1p1)
	(= (need-for-catalyzed-association DMP1 cdk46p3-cycDp1 DMP1p1) 1)
	(= (need-for-catalyzed-association cdk46p3-cycDp1 DMP1 DMP1p1) 4)
	(= (prod-by-catalyzed-association DMP1 cdk46p3-cycDp1 DMP1p1) 3)
	(association-reaction DMP1 cycD DMP1-cycD)
	(= (need-for-association DMP1 cycD DMP1-cycD) 4)
	(= (need-for-association cycD DMP1 DMP1-cycD) 2)
	(= (prod-by-association DMP1 cycD DMP1-cycD) 2)
	(association-reaction DMP1 cycDp1 DMP1-cycDp1)
	(= (need-for-association DMP1 cycDp1 DMP1-cycDp1) 4)
	(= (need-for-association cycDp1 DMP1 DMP1-cycDp1) 3)
	(= (prod-by-association DMP1 cycDp1 DMP1-cycDp1) 1)
	(association-reaction DMP1 gp19ARF DMP1-gp19ARF)
	(= (need-for-association DMP1 gp19ARF DMP1-gp19ARF) 4)
	(= (need-for-association gp19ARF DMP1 DMP1-gp19ARF) 3)
	(= (prod-by-association DMP1 gp19ARF DMP1-gp19ARF) 4)
	(association-reaction DMP1p1 cycD DMP1p1-cycD)
	(= (need-for-association DMP1p1 cycD DMP1p1-cycD) 1)
	(= (need-for-association cycD DMP1p1 DMP1p1-cycD) 1)
	(= (prod-by-association DMP1p1 cycD DMP1p1-cycD) 3)
	(association-reaction DMP1p1 cycDp1 DMP1p1-cycDp1)
	(= (need-for-association DMP1p1 cycDp1 DMP1p1-cycDp1) 2)
	(= (need-for-association cycDp1 DMP1p1 DMP1p1-cycDp1) 2)
	(= (prod-by-association DMP1p1 cycDp1 DMP1p1-cycDp1) 4)
	(association-reaction DMP1p1 gp19ARF DMP1p1-gp19ARF)
	(= (need-for-association DMP1p1 gp19ARF DMP1p1-gp19ARF) 4)
	(= (need-for-association gp19ARF DMP1p1 DMP1p1-gp19ARF) 1)
	(= (prod-by-association DMP1p1 gp19ARF DMP1p1-gp19ARF) 3)
	(synthesis-reaction DMP1p1-gp19ARF p19ARF) 
	(= (need-for-synthesis DMP1p1-gp19ARF p19ARF) 2)
	(= (prod-by-synthesis DMP1p1-gp19ARF p19ARF) 1)
	(synthesis-reaction E2F13-DP12-gE2 c-Myc) 
	(= (need-for-synthesis E2F13-DP12-gE2 c-Myc) 2)
	(= (prod-by-synthesis E2F13-DP12-gE2 c-Myc) 4)
	(synthesis-reaction E2F13-DP12-gE2 cycA) 
	(= (need-for-synthesis E2F13-DP12-gE2 cycA) 4)
	(= (prod-by-synthesis E2F13-DP12-gE2 cycA) 2)
	(synthesis-reaction E2F13-DP12-gE2 cycD) 
	(= (need-for-synthesis E2F13-DP12-gE2 cycD) 1)
	(= (prod-by-synthesis E2F13-DP12-gE2 cycD) 1)
	(synthesis-reaction E2F13-DP12-gE2 cycDp1) 
	(= (need-for-synthesis E2F13-DP12-gE2 cycDp1) 4)
	(= (prod-by-synthesis E2F13-DP12-gE2 cycDp1) 4)
	(synthesis-reaction E2F13-DP12-gE2 cycE) 
	(= (need-for-synthesis E2F13-DP12-gE2 cycE) 1)
	(= (prod-by-synthesis E2F13-DP12-gE2 cycE) 4)
	(synthesis-reaction E2F13-DP12-gE2 cycEp1) 
	(= (need-for-synthesis E2F13-DP12-gE2 cycEp1) 2)
	(= (prod-by-synthesis E2F13-DP12-gE2 cycEp1) 4)
	(association-reaction E2F13-DP12 gE2 E2F13-DP12-gE2)
	(= (need-for-association E2F13-DP12 gE2 E2F13-DP12-gE2) 1)
	(= (need-for-association gE2 E2F13-DP12 E2F13-DP12-gE2) 4)
	(= (prod-by-association E2F13-DP12 gE2 E2F13-DP12-gE2) 3)
	(synthesis-reaction E2F13-DP12-gE2 p107) 
	(= (need-for-synthesis E2F13-DP12-gE2 p107) 3)
	(= (prod-by-synthesis E2F13-DP12-gE2 p107) 4)
	(synthesis-reaction E2F13-DP12-gE2 p107p1) 
	(= (need-for-synthesis E2F13-DP12-gE2 p107p1) 2)
	(= (prod-by-synthesis E2F13-DP12-gE2 p107p1) 1)
	(synthesis-reaction E2F13-DP12-gE2 p19ARF) 
	(= (need-for-synthesis E2F13-DP12-gE2 p19ARF) 3)
	(= (prod-by-synthesis E2F13-DP12-gE2 p19ARF) 2)
	(synthesis-reaction E2F13-DP12-gE2 pol) 
	(= (need-for-synthesis E2F13-DP12-gE2 pol) 1)
	(= (prod-by-synthesis E2F13-DP12-gE2 pol) 2)
	(synthesis-reaction E2F13p1-DP12-gE2 c-Myc) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 c-Myc) 3)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 c-Myc) 3)
	(synthesis-reaction E2F13p1-DP12-gE2 cycA) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 cycA) 1)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 cycA) 2)
	(synthesis-reaction E2F13p1-DP12-gE2 cycD) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 cycD) 3)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 cycD) 3)
	(synthesis-reaction E2F13p1-DP12-gE2 cycDp1) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 cycDp1) 3)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 cycDp1) 3)
	(synthesis-reaction E2F13p1-DP12-gE2 cycE) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 cycE) 1)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 cycE) 3)
	(synthesis-reaction E2F13p1-DP12-gE2 cycEp1) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 cycEp1) 2)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 cycEp1) 2)
	(association-reaction E2F13p1-DP12 gE2 E2F13p1-DP12-gE2)
	(= (need-for-association E2F13p1-DP12 gE2 E2F13p1-DP12-gE2) 3)
	(= (need-for-association gE2 E2F13p1-DP12 E2F13p1-DP12-gE2) 2)
	(= (prod-by-association E2F13p1-DP12 gE2 E2F13p1-DP12-gE2) 1)
	(synthesis-reaction E2F13p1-DP12-gE2 p107) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 p107) 2)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 p107) 2)
	(synthesis-reaction E2F13p1-DP12-gE2 p107p1) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 p107p1) 4)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 p107p1) 3)
	(synthesis-reaction E2F13p1-DP12-gE2 p19ARF) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 p19ARF) 1)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 p19ARF) 4)
	(synthesis-reaction E2F13p1-DP12-gE2 pol) 
	(= (need-for-synthesis E2F13p1-DP12-gE2 pol) 2)
	(= (prod-by-synthesis E2F13p1-DP12-gE2 pol) 4)
	(association-reaction HDAC1-p107-E2F4p1-DP12 gE2 HDAC1-p107-E2F4p1-DP12-gE2)
	(= (need-for-association HDAC1-p107-E2F4p1-DP12 gE2 HDAC1-p107-E2F4p1-DP12-gE2) 2)
	(= (need-for-association gE2 HDAC1-p107-E2F4p1-DP12 HDAC1-p107-E2F4p1-DP12-gE2) 1)
	(= (prod-by-association HDAC1-p107-E2F4p1-DP12 gE2 HDAC1-p107-E2F4p1-DP12-gE2) 1)
	(association-reaction HDAC1-p130-E2F4p1-DP12 gE2 HDAC1-p130-E2F4p1-DP12-gE2)
	(= (need-for-association HDAC1-p130-E2F4p1-DP12 gE2 HDAC1-p130-E2F4p1-DP12-gE2) 2)
	(= (need-for-association gE2 HDAC1-p130-E2F4p1-DP12 HDAC1-p130-E2F4p1-DP12-gE2) 4)
	(= (prod-by-association HDAC1-p130-E2F4p1-DP12 gE2 HDAC1-p130-E2F4p1-DP12-gE2) 3)
	(association-reaction HDAC1-pRb-E2F13-DP12 gE2 HDAC1-pRb-E2F13-DP12-gE2)
	(= (need-for-association HDAC1-pRb-E2F13-DP12 gE2 HDAC1-pRb-E2F13-DP12-gE2) 3)
	(= (need-for-association gE2 HDAC1-pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12-gE2) 1)
	(= (prod-by-association HDAC1-pRb-E2F13-DP12 gE2 HDAC1-pRb-E2F13-DP12-gE2) 1)
	(association-reaction HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12)
	(= (need-for-association HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12) 1)
	(= (need-for-association pRb-E2F13-DP12 HDAC1 HDAC1-pRb-E2F13-DP12) 1)
	(= (prod-by-association HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12) 3)
	(association-reaction HDAC1 pRb-E2F13-DP12p1 HDAC1-pRb-E2F13-DP12p1)
	(= (need-for-association HDAC1 pRb-E2F13-DP12p1 HDAC1-pRb-E2F13-DP12p1) 3)
	(= (need-for-association pRb-E2F13-DP12p1 HDAC1 HDAC1-pRb-E2F13-DP12p1) 3)
	(= (prod-by-association HDAC1 pRb-E2F13-DP12p1 HDAC1-pRb-E2F13-DP12p1) 1)
	(association-reaction HDAC1-pRb-E2F13p1-DP12 gE2 HDAC1-pRb-E2F13p1-DP12-gE2)
	(= (need-for-association HDAC1-pRb-E2F13p1-DP12 gE2 HDAC1-pRb-E2F13p1-DP12-gE2) 1)
	(= (need-for-association gE2 HDAC1-pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12-gE2) 3)
	(= (prod-by-association HDAC1-pRb-E2F13p1-DP12 gE2 HDAC1-pRb-E2F13p1-DP12-gE2) 3)
	(association-reaction HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12)
	(= (need-for-association HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12) 2)
	(= (need-for-association pRb-E2F13p1-DP12 HDAC1 HDAC1-pRb-E2F13p1-DP12) 4)
	(= (prod-by-association HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12) 1)
	(association-reaction HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1)
	(= (need-for-association HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1) 3)
	(= (need-for-association pRb-E2F13p1-DP12p1 HDAC1 HDAC1-pRb-E2F13p1-DP12p1) 1)
	(= (prod-by-association HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1) 2)
	(association-reaction HDAC1 pRb-E2F4p1-DP12 HDAC1-pRb-E2F4p1-DP12)
	(= (need-for-association HDAC1 pRb-E2F4p1-DP12 HDAC1-pRb-E2F4p1-DP12) 4)
	(= (need-for-association pRb-E2F4p1-DP12 HDAC1 HDAC1-pRb-E2F4p1-DP12) 4)
	(= (prod-by-association HDAC1 pRb-E2F4p1-DP12 HDAC1-pRb-E2F4p1-DP12) 1)
	(association-reaction HDAC1-pRbp1-E2F13-DP12 gE2 HDAC1-pRbp1-E2F13-DP12-gE2)
	(= (need-for-association HDAC1-pRbp1-E2F13-DP12 gE2 HDAC1-pRbp1-E2F13-DP12-gE2) 4)
	(= (need-for-association gE2 HDAC1-pRbp1-E2F13-DP12 HDAC1-pRbp1-E2F13-DP12-gE2) 4)
	(= (prod-by-association HDAC1-pRbp1-E2F13-DP12 gE2 HDAC1-pRbp1-E2F13-DP12-gE2) 2)
	(association-reaction HDAC1-pRbp1-E2F13p1-DP12 gE2 HDAC1-pRbp1-E2F13p1-DP12-gE2)
	(= (need-for-association HDAC1-pRbp1-E2F13p1-DP12 gE2 HDAC1-pRbp1-E2F13p1-DP12-gE2) 3)
	(= (need-for-association gE2 HDAC1-pRbp1-E2F13p1-DP12 HDAC1-pRbp1-E2F13p1-DP12-gE2) 1)
	(= (prod-by-association HDAC1-pRbp1-E2F13p1-DP12 gE2 HDAC1-pRbp1-E2F13p1-DP12-gE2) 3)
	(synthesis-reaction Jun-c-Fos-gERCC1 ERCC1) 
	(= (need-for-synthesis Jun-c-Fos-gERCC1 ERCC1) 4)
	(= (prod-by-synthesis Jun-c-Fos-gERCC1 ERCC1) 3)
	(association-reaction Jun-c-Fos gERCC1 Jun-c-Fos-gERCC1)
	(= (need-for-association Jun-c-Fos gERCC1 Jun-c-Fos-gERCC1) 2)
	(= (need-for-association gERCC1 Jun-c-Fos Jun-c-Fos-gERCC1) 2)
	(= (prod-by-association Jun-c-Fos gERCC1 Jun-c-Fos-gERCC1) 1)
	(association-reaction Jun c-Fos Jun-c-Fos)
	(= (need-for-association Jun c-Fos Jun-c-Fos) 2)
	(= (need-for-association c-Fos Jun Jun-c-Fos) 2)
	(= (prod-by-association Jun c-Fos Jun-c-Fos) 1)
	(association-reaction m1433 cdc25Cp1p2 m1433-cdc25Cp1p2)
	(= (need-for-association m1433 cdc25Cp1p2 m1433-cdc25Cp1p2) 2)
	(= (need-for-association cdc25Cp1p2 m1433 m1433-cdc25Cp1p2) 4)
	(= (prod-by-association m1433 cdc25Cp1p2 m1433-cdc25Cp1p2) 3)
	(association-reaction m1433 cdc25Cp2 m1433-cdc25Cp2)
	(= (need-for-association m1433 cdc25Cp2 m1433-cdc25Cp2) 4)
	(= (need-for-association cdc25Cp2 m1433 m1433-cdc25Cp2) 1)
	(= (prod-by-association m1433 cdc25Cp2 m1433-cdc25Cp2) 3)
	(association-reaction Mdm2 E2F13-DP12 Mdm2-E2F13-DP12)
	(= (need-for-association Mdm2 E2F13-DP12 Mdm2-E2F13-DP12) 3)
	(= (need-for-association E2F13-DP12 Mdm2 Mdm2-E2F13-DP12) 3)
	(= (prod-by-association Mdm2 E2F13-DP12 Mdm2-E2F13-DP12) 4)
	(association-reaction Mdm2 E2F13-DP12p1 Mdm2-E2F13-DP12p1)
	(= (need-for-association Mdm2 E2F13-DP12p1 Mdm2-E2F13-DP12p1) 2)
	(= (need-for-association E2F13-DP12p1 Mdm2 Mdm2-E2F13-DP12p1) 4)
	(= (prod-by-association Mdm2 E2F13-DP12p1 Mdm2-E2F13-DP12p1) 2)
	(association-reaction Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12)
	(= (need-for-association Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12) 2)
	(= (need-for-association E2F13p1-DP12 Mdm2 Mdm2-E2F13p1-DP12) 1)
	(= (prod-by-association Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12) 1)
	(association-reaction Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1)
	(= (need-for-association Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1) 2)
	(= (need-for-association E2F13p1-DP12p1 Mdm2 Mdm2-E2F13p1-DP12p1) 1)
	(= (prod-by-association Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1) 4)
	(association-reaction Mdm2 pRb Mdm2-pRb)
	(= (need-for-association Mdm2 pRb Mdm2-pRb) 1)
	(= (need-for-association pRb Mdm2 Mdm2-pRb) 3)
	(= (prod-by-association Mdm2 pRb Mdm2-pRb) 3)
	(association-reaction Mdm2 pRbp1 Mdm2-pRbp1)
	(= (need-for-association Mdm2 pRbp1 Mdm2-pRbp1) 1)
	(= (need-for-association pRbp1 Mdm2 Mdm2-pRbp1) 1)
	(= (prod-by-association Mdm2 pRbp1 Mdm2-pRbp1) 2)
	(association-reaction p21 cdk2p1-cycA p21-cdk2p1-cycA)
	(= (need-for-association p21 cdk2p1-cycA p21-cdk2p1-cycA) 3)
	(= (need-for-association cdk2p1-cycA p21 p21-cdk2p1-cycA) 2)
	(= (prod-by-association p21 cdk2p1-cycA p21-cdk2p1-cycA) 3)
	(association-reaction p21 cdk2p1-cycEp1 p21-cdk2p1-cycEp1)
	(= (need-for-association p21 cdk2p1-cycEp1 p21-cdk2p1-cycEp1) 3)
	(= (need-for-association cdk2p1-cycEp1 p21 p21-cdk2p1-cycEp1) 3)
	(= (prod-by-association p21 cdk2p1-cycEp1 p21-cdk2p1-cycEp1) 4)
	(association-reaction p21 cdk2p1-cycE p21-cdk2p1-cycE)
	(= (need-for-association p21 cdk2p1-cycE p21-cdk2p1-cycE) 3)
	(= (need-for-association cdk2p1-cycE p21 p21-cdk2p1-cycE) 4)
	(= (prod-by-association p21 cdk2p1-cycE p21-cdk2p1-cycE) 4)
	(association-reaction p21 cdk2p1p2-cycA p21-cdk2p1p2-cycA)
	(= (need-for-association p21 cdk2p1p2-cycA p21-cdk2p1p2-cycA) 1)
	(= (need-for-association cdk2p1p2-cycA p21 p21-cdk2p1p2-cycA) 3)
	(= (prod-by-association p21 cdk2p1p2-cycA p21-cdk2p1p2-cycA) 4)
	(association-reaction p21 cdk2p1p2-cycEp1 p21-cdk2p1p2-cycEp1)
	(= (need-for-association p21 cdk2p1p2-cycEp1 p21-cdk2p1p2-cycEp1) 3)
	(= (need-for-association cdk2p1p2-cycEp1 p21 p21-cdk2p1p2-cycEp1) 1)
	(= (prod-by-association p21 cdk2p1p2-cycEp1 p21-cdk2p1p2-cycEp1) 2)
	(association-reaction p21 cdk2p1p2-cycE p21-cdk2p1p2-cycE)
	(= (need-for-association p21 cdk2p1p2-cycE p21-cdk2p1p2-cycE) 2)
	(= (need-for-association cdk2p1p2-cycE p21 p21-cdk2p1p2-cycE) 3)
	(= (prod-by-association p21 cdk2p1p2-cycE p21-cdk2p1p2-cycE) 1)
	(association-reaction p21 Gadd45 p21-Gadd45)
	(= (need-for-association p21 Gadd45 p21-Gadd45) 3)
	(= (need-for-association Gadd45 p21 p21-Gadd45) 4)
	(= (prod-by-association p21 Gadd45 p21-Gadd45) 2)
	(association-reaction p27 cdk2p1-cycA p27-cdk2p1-cycA)
	(= (need-for-association p27 cdk2p1-cycA p27-cdk2p1-cycA) 3)
	(= (need-for-association cdk2p1-cycA p27 p27-cdk2p1-cycA) 1)
	(= (prod-by-association p27 cdk2p1-cycA p27-cdk2p1-cycA) 2)
	(association-reaction p27 cdk2p1-cycEp1 p27-cdk2p1-cycEp1)
	(= (need-for-association p27 cdk2p1-cycEp1 p27-cdk2p1-cycEp1) 3)
	(= (need-for-association cdk2p1-cycEp1 p27 p27-cdk2p1-cycEp1) 1)
	(= (prod-by-association p27 cdk2p1-cycEp1 p27-cdk2p1-cycEp1) 4)
	(association-reaction p27 cdk2p1-cycE p27-cdk2p1-cycE)
	(= (need-for-association p27 cdk2p1-cycE p27-cdk2p1-cycE) 1)
	(= (need-for-association cdk2p1-cycE p27 p27-cdk2p1-cycE) 2)
	(= (prod-by-association p27 cdk2p1-cycE p27-cdk2p1-cycE) 4)
	(association-reaction p27 cdk2p1p2-cycA p27-cdk2p1p2-cycA)
	(= (need-for-association p27 cdk2p1p2-cycA p27-cdk2p1p2-cycA) 2)
	(= (need-for-association cdk2p1p2-cycA p27 p27-cdk2p1p2-cycA) 4)
	(= (prod-by-association p27 cdk2p1p2-cycA p27-cdk2p1p2-cycA) 1)
	(association-reaction p27 cdk2p1p2-cycEp1 p27-cdk2p1p2-cycEp1)
	(= (need-for-association p27 cdk2p1p2-cycEp1 p27-cdk2p1p2-cycEp1) 4)
	(= (need-for-association cdk2p1p2-cycEp1 p27 p27-cdk2p1p2-cycEp1) 3)
	(= (prod-by-association p27 cdk2p1p2-cycEp1 p27-cdk2p1p2-cycEp1) 3)
	(association-reaction p27 cdk2p1p2-cycE p27-cdk2p1p2-cycE)
	(= (need-for-association p27 cdk2p1p2-cycE p27-cdk2p1p2-cycE) 3)
	(= (need-for-association cdk2p1p2-cycE p27 p27-cdk2p1p2-cycE) 1)
	(= (prod-by-association p27 cdk2p1p2-cycE p27-cdk2p1p2-cycE) 2)
	(synthesis-reaction p53 c-Fos) 
	(= (need-for-synthesis p53 c-Fos) 2)
	(= (prod-by-synthesis p53 c-Fos) 2)
	(synthesis-reaction p53 Gadd45) 
	(= (need-for-synthesis p53 Gadd45) 1)
	(= (prod-by-synthesis p53 Gadd45) 1)
	(synthesis-reaction p53 Mdm2) 
	(= (need-for-synthesis p53 Mdm2) 4)
	(= (prod-by-synthesis p53 Mdm2) 1)
	(synthesis-reaction p53p1 c-Fos) 
	(= (need-for-synthesis p53p1 c-Fos) 3)
	(= (prod-by-synthesis p53p1 c-Fos) 2)
	(synthesis-reaction p53p1 Gadd45) 
	(= (need-for-synthesis p53p1 Gadd45) 3)
	(= (prod-by-synthesis p53p1 Gadd45) 3)
	(synthesis-reaction p53p1 Mdm2) 
	(= (need-for-synthesis p53p1 Mdm2) 4)
	(= (prod-by-synthesis p53p1 Mdm2) 3)
	(synthesis-reaction p53p1 p21) 
	(= (need-for-synthesis p53p1 p21) 4)
	(= (prod-by-synthesis p53p1 p21) 3)
	(synthesis-reaction p53 p21) 
	(= (need-for-synthesis p53 p21) 3)
	(= (prod-by-synthesis p53 p21) 2)
	(association-reaction p57 cdk2p1-cycA p57-cdk2p1-cycA)
	(= (need-for-association p57 cdk2p1-cycA p57-cdk2p1-cycA) 1)
	(= (need-for-association cdk2p1-cycA p57 p57-cdk2p1-cycA) 4)
	(= (prod-by-association p57 cdk2p1-cycA p57-cdk2p1-cycA) 1)
	(association-reaction p57 cdk2p1-cycEp1 p57-cdk2p1-cycEp1)
	(= (need-for-association p57 cdk2p1-cycEp1 p57-cdk2p1-cycEp1) 1)
	(= (need-for-association cdk2p1-cycEp1 p57 p57-cdk2p1-cycEp1) 1)
	(= (prod-by-association p57 cdk2p1-cycEp1 p57-cdk2p1-cycEp1) 1)
	(association-reaction p57 cdk2p1-cycE p57-cdk2p1-cycE)
	(= (need-for-association p57 cdk2p1-cycE p57-cdk2p1-cycE) 2)
	(= (need-for-association cdk2p1-cycE p57 p57-cdk2p1-cycE) 4)
	(= (prod-by-association p57 cdk2p1-cycE p57-cdk2p1-cycE) 1)
	(association-reaction p57 cdk2p1p2-cycA p57-cdk2p1p2-cycA)
	(= (need-for-association p57 cdk2p1p2-cycA p57-cdk2p1p2-cycA) 1)
	(= (need-for-association cdk2p1p2-cycA p57 p57-cdk2p1p2-cycA) 2)
	(= (prod-by-association p57 cdk2p1p2-cycA p57-cdk2p1p2-cycA) 4)
	(association-reaction p57 cdk2p1p2-cycEp1 p57-cdk2p1p2-cycEp1)
	(= (need-for-association p57 cdk2p1p2-cycEp1 p57-cdk2p1p2-cycEp1) 3)
	(= (need-for-association cdk2p1p2-cycEp1 p57 p57-cdk2p1p2-cycEp1) 3)
	(= (prod-by-association p57 cdk2p1p2-cycEp1 p57-cdk2p1p2-cycEp1) 1)
	(association-reaction p57 cdk2p1p2-cycE p57-cdk2p1p2-cycE)
	(= (need-for-association p57 cdk2p1p2-cycE p57-cdk2p1p2-cycE) 1)
	(= (need-for-association cdk2p1p2-cycE p57 p57-cdk2p1p2-cycE) 4)
	(= (prod-by-association p57 cdk2p1p2-cycE p57-cdk2p1p2-cycE) 1)
	(synthesis-reaction pRb-AP2-gE-c Ecadherin) 
	(= (need-for-synthesis pRb-AP2-gE-c Ecadherin) 1)
	(= (prod-by-synthesis pRb-AP2-gE-c Ecadherin) 3)
	(association-reaction pRb-AP2 gE-c pRb-AP2-gE-c)
	(= (need-for-association pRb-AP2 gE-c pRb-AP2-gE-c) 2)
	(= (need-for-association gE-c pRb-AP2 pRb-AP2-gE-c) 3)
	(= (prod-by-association pRb-AP2 gE-c pRb-AP2-gE-c) 4)
	(association-reaction pRb AP2 pRb-AP2)
	(= (need-for-association pRb AP2 pRb-AP2) 4)
	(= (need-for-association AP2 pRb pRb-AP2) 2)
	(= (prod-by-association pRb AP2 pRb-AP2) 4)
	(catalyzed-association-reaction pRb cdk46p3-cycDp1 pRbp1)
	(= (need-for-catalyzed-association pRb cdk46p3-cycDp1 pRbp1) 2)
	(= (need-for-catalyzed-association cdk46p3-cycDp1 pRb pRbp1) 1)
	(= (prod-by-catalyzed-association pRb cdk46p3-cycDp1 pRbp1) 2)
	(association-reaction pRb-E2F13-DP12 gE2 pRb-E2F13-DP12-gE2)
	(= (need-for-association pRb-E2F13-DP12 gE2 pRb-E2F13-DP12-gE2) 1)
	(= (need-for-association gE2 pRb-E2F13-DP12 pRb-E2F13-DP12-gE2) 2)
	(= (prod-by-association pRb-E2F13-DP12 gE2 pRb-E2F13-DP12-gE2) 2)
	(association-reaction pRb-E2F13-DP12p1 gE2 pRb-E2F13-DP12p1-gE2)
	(= (need-for-association pRb-E2F13-DP12p1 gE2 pRb-E2F13-DP12p1-gE2) 4)
	(= (need-for-association gE2 pRb-E2F13-DP12p1 pRb-E2F13-DP12p1-gE2) 3)
	(= (prod-by-association pRb-E2F13-DP12p1 gE2 pRb-E2F13-DP12p1-gE2) 2)
	(association-reaction pRb E2F13-DP12p1 pRb-E2F13-DP12p1)
	(= (need-for-association pRb E2F13-DP12p1 pRb-E2F13-DP12p1) 4)
	(= (need-for-association E2F13-DP12p1 pRb pRb-E2F13-DP12p1) 3)
	(= (prod-by-association pRb E2F13-DP12p1 pRb-E2F13-DP12p1) 3)
	(association-reaction pRb E2F13-DP12 pRb-E2F13-DP12)
	(= (need-for-association pRb E2F13-DP12 pRb-E2F13-DP12) 3)
	(= (need-for-association E2F13-DP12 pRb pRb-E2F13-DP12) 3)
	(= (prod-by-association pRb E2F13-DP12 pRb-E2F13-DP12) 3)
	(association-reaction pRb-E2F13p1-DP12 gE2 pRb-E2F13p1-DP12-gE2)
	(= (need-for-association pRb-E2F13p1-DP12 gE2 pRb-E2F13p1-DP12-gE2) 1)
	(= (need-for-association gE2 pRb-E2F13p1-DP12 pRb-E2F13p1-DP12-gE2) 2)
	(= (prod-by-association pRb-E2F13p1-DP12 gE2 pRb-E2F13p1-DP12-gE2) 1)
	(association-reaction pRb-E2F13p1-DP12p1 gE2 pRb-E2F13p1-DP12p1-gE2)
	(= (need-for-association pRb-E2F13p1-DP12p1 gE2 pRb-E2F13p1-DP12p1-gE2) 3)
	(= (need-for-association gE2 pRb-E2F13p1-DP12p1 pRb-E2F13p1-DP12p1-gE2) 3)
	(= (prod-by-association pRb-E2F13p1-DP12p1 gE2 pRb-E2F13p1-DP12p1-gE2) 1)
	(association-reaction pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1)
	(= (need-for-association pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1) 2)
	(= (need-for-association E2F13p1-DP12p1 pRb pRb-E2F13p1-DP12p1) 3)
	(= (prod-by-association pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1) 2)
	(association-reaction pRb E2F13p1-DP12 pRb-E2F13p1-DP12)
	(= (need-for-association pRb E2F13p1-DP12 pRb-E2F13p1-DP12) 4)
	(= (need-for-association E2F13p1-DP12 pRb pRb-E2F13p1-DP12) 4)
	(= (prod-by-association pRb E2F13p1-DP12 pRb-E2F13p1-DP12) 4)
	(association-reaction pRb-E2F4p1-DP12 gE2 pRb-E2F4p1-DP12-gE2)
	(= (need-for-association pRb-E2F4p1-DP12 gE2 pRb-E2F4p1-DP12-gE2) 4)
	(= (need-for-association gE2 pRb-E2F4p1-DP12 pRb-E2F4p1-DP12-gE2) 4)
	(= (prod-by-association pRb-E2F4p1-DP12 gE2 pRb-E2F4p1-DP12-gE2) 1)
	(synthesis-reaction pRb-Jun-c-Fos-gERCC1 ERCC1) 
	(= (need-for-synthesis pRb-Jun-c-Fos-gERCC1 ERCC1) 3)
	(= (prod-by-synthesis pRb-Jun-c-Fos-gERCC1 ERCC1) 1)
	(association-reaction pRb-Jun-c-Fos gERCC1 pRb-Jun-c-Fos-gERCC1)
	(= (need-for-association pRb-Jun-c-Fos gERCC1 pRb-Jun-c-Fos-gERCC1) 2)
	(= (need-for-association gERCC1 pRb-Jun-c-Fos pRb-Jun-c-Fos-gERCC1) 4)
	(= (prod-by-association pRb-Jun-c-Fos gERCC1 pRb-Jun-c-Fos-gERCC1) 1)
	(association-reaction pRb-Jun c-Fos pRb-Jun-c-Fos)
	(= (need-for-association pRb-Jun c-Fos pRb-Jun-c-Fos) 3)
	(= (need-for-association c-Fos pRb-Jun pRb-Jun-c-Fos) 1)
	(= (prod-by-association pRb-Jun c-Fos pRb-Jun-c-Fos) 4)
	(association-reaction pRb Jun pRb-Jun)
	(= (need-for-association pRb Jun pRb-Jun) 1)
	(= (need-for-association Jun pRb pRb-Jun) 2)
	(= (prod-by-association pRb Jun pRb-Jun) 3)
	(synthesis-reaction pRbp1-AP2-gE-c Ecadherin) 
	(= (need-for-synthesis pRbp1-AP2-gE-c Ecadherin) 3)
	(= (prod-by-synthesis pRbp1-AP2-gE-c Ecadherin) 4)
	(association-reaction pRbp1-AP2 gE-c pRbp1-AP2-gE-c)
	(= (need-for-association pRbp1-AP2 gE-c pRbp1-AP2-gE-c) 2)
	(= (need-for-association gE-c pRbp1-AP2 pRbp1-AP2-gE-c) 2)
	(= (prod-by-association pRbp1-AP2 gE-c pRbp1-AP2-gE-c) 2)
	(association-reaction pRbp1 AP2 pRbp1-AP2)
	(= (need-for-association pRbp1 AP2 pRbp1-AP2) 2)
	(= (need-for-association AP2 pRbp1 pRbp1-AP2) 3)
	(= (prod-by-association pRbp1 AP2 pRbp1-AP2) 2)
	(association-reaction pRbp1-E2F13-DP12 gE2 pRbp1-E2F13-DP12-gE2)
	(= (need-for-association pRbp1-E2F13-DP12 gE2 pRbp1-E2F13-DP12-gE2) 4)
	(= (need-for-association gE2 pRbp1-E2F13-DP12 pRbp1-E2F13-DP12-gE2) 1)
	(= (prod-by-association pRbp1-E2F13-DP12 gE2 pRbp1-E2F13-DP12-gE2) 3)
	(association-reaction pRbp1-E2F13-DP12p1 gE2 pRbp1-E2F13-DP12p1-gE2)
	(= (need-for-association pRbp1-E2F13-DP12p1 gE2 pRbp1-E2F13-DP12p1-gE2) 1)
	(= (need-for-association gE2 pRbp1-E2F13-DP12p1 pRbp1-E2F13-DP12p1-gE2) 4)
	(= (prod-by-association pRbp1-E2F13-DP12p1 gE2 pRbp1-E2F13-DP12p1-gE2) 4)
	(association-reaction pRbp1 E2F13-DP12p1 pRbp1-E2F13-DP12p1)
	(= (need-for-association pRbp1 E2F13-DP12p1 pRbp1-E2F13-DP12p1) 4)
	(= (need-for-association E2F13-DP12p1 pRbp1 pRbp1-E2F13-DP12p1) 3)
	(= (prod-by-association pRbp1 E2F13-DP12p1 pRbp1-E2F13-DP12p1) 3)
	(association-reaction pRbp1 E2F13-DP12 pRbp1-E2F13-DP12)
	(= (need-for-association pRbp1 E2F13-DP12 pRbp1-E2F13-DP12) 3)
	(= (need-for-association E2F13-DP12 pRbp1 pRbp1-E2F13-DP12) 2)
	(= (prod-by-association pRbp1 E2F13-DP12 pRbp1-E2F13-DP12) 4)
	(association-reaction pRbp1-E2F13p1-DP12 gE2 pRbp1-E2F13p1-DP12-gE2)
	(= (need-for-association pRbp1-E2F13p1-DP12 gE2 pRbp1-E2F13p1-DP12-gE2) 1)
	(= (need-for-association gE2 pRbp1-E2F13p1-DP12 pRbp1-E2F13p1-DP12-gE2) 3)
	(= (prod-by-association pRbp1-E2F13p1-DP12 gE2 pRbp1-E2F13p1-DP12-gE2) 1)
	(association-reaction pRbp1-E2F13p1-DP12p1 gE2 pRbp1-E2F13p1-DP12p1-gE2)
	(= (need-for-association pRbp1-E2F13p1-DP12p1 gE2 pRbp1-E2F13p1-DP12p1-gE2) 4)
	(= (need-for-association gE2 pRbp1-E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1-gE2) 3)
	(= (prod-by-association pRbp1-E2F13p1-DP12p1 gE2 pRbp1-E2F13p1-DP12p1-gE2) 3)
	(association-reaction pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1)
	(= (need-for-association pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1) 4)
	(= (need-for-association E2F13p1-DP12p1 pRbp1 pRbp1-E2F13p1-DP12p1) 3)
	(= (prod-by-association pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1) 4)
	(association-reaction pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12)
	(= (need-for-association pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12) 1)
	(= (need-for-association E2F13p1-DP12 pRbp1 pRbp1-E2F13p1-DP12) 1)
	(= (prod-by-association pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12) 2)
	(synthesis-reaction pRbp1-Jun-c-Fos-gERCC1 ERCC1) 
	(= (need-for-synthesis pRbp1-Jun-c-Fos-gERCC1 ERCC1) 4)
	(= (prod-by-synthesis pRbp1-Jun-c-Fos-gERCC1 ERCC1) 2)
	(association-reaction pRbp1-Jun-c-Fos gERCC1 pRbp1-Jun-c-Fos-gERCC1)
	(= (need-for-association pRbp1-Jun-c-Fos gERCC1 pRbp1-Jun-c-Fos-gERCC1) 3)
	(= (need-for-association gERCC1 pRbp1-Jun-c-Fos pRbp1-Jun-c-Fos-gERCC1) 1)
	(= (prod-by-association pRbp1-Jun-c-Fos gERCC1 pRbp1-Jun-c-Fos-gERCC1) 3)
	(association-reaction pRbp1-Jun c-Fos pRbp1-Jun-c-Fos)
	(= (need-for-association pRbp1-Jun c-Fos pRbp1-Jun-c-Fos) 2)
	(= (need-for-association c-Fos pRbp1-Jun pRbp1-Jun-c-Fos) 3)
	(= (prod-by-association pRbp1-Jun c-Fos pRbp1-Jun-c-Fos) 2)
	(association-reaction pRbp1 Jun pRbp1-Jun)
	(= (need-for-association pRbp1 Jun pRbp1-Jun) 2)
	(= (need-for-association Jun pRbp1 pRbp1-Jun) 1)
	(= (prod-by-association pRbp1 Jun pRbp1-Jun) 2)
	(association-reaction RPA cycA RPA-cycA)
	(= (need-for-association RPA cycA RPA-cycA) 1)
	(= (need-for-association cycA RPA RPA-cycA) 4)
	(= (prod-by-association RPA cycA RPA-cycA) 2)
	(association-reaction Skp2 cdk2p1-cycA Skp2-cdk2p1-cycA)
	(= (need-for-association Skp2 cdk2p1-cycA Skp2-cdk2p1-cycA) 4)
	(= (need-for-association cdk2p1-cycA Skp2 Skp2-cdk2p1-cycA) 2)
	(= (prod-by-association Skp2 cdk2p1-cycA Skp2-cdk2p1-cycA) 4)
	(association-reaction Skp2 cdk2p1p2-cycA Skp2-cdk2p1p2-cycA)
	(= (need-for-association Skp2 cdk2p1p2-cycA Skp2-cdk2p1p2-cycA) 1)
	(= (need-for-association cdk2p1p2-cycA Skp2 Skp2-cdk2p1p2-cycA) 1)
	(= (prod-by-association Skp2 cdk2p1p2-cycA Skp2-cdk2p1p2-cycA) 1)
	(association-reaction SP1 E2F13 SP1-E2F13)
	(= (need-for-association SP1 E2F13 SP1-E2F13) 3)
	(= (need-for-association E2F13 SP1 SP1-E2F13) 1)
	(= (prod-by-association SP1 E2F13 SP1-E2F13) 4)
	(association-reaction SP1 p107p1 SP1-p107p1)
	(= (need-for-association SP1 p107p1 SP1-p107p1) 2)
	(= (need-for-association p107p1 SP1 SP1-p107p1) 4)
	(= (prod-by-association SP1 p107p1 SP1-p107p1) 4)
	(association-reaction SP1 p107 SP1-p107)
	(= (need-for-association SP1 p107 SP1-p107) 4)
	(= (need-for-association p107 SP1 SP1-p107) 3)
	(= (prod-by-association SP1 p107 SP1-p107) 4)
	(catalyzed-association-reaction Wee1 cdk1p3-cycA Wee1p1)
	(= (need-for-catalyzed-association Wee1 cdk1p3-cycA Wee1p1) 4)
	(= (need-for-catalyzed-association cdk1p3-cycA Wee1 Wee1p1) 4)
	(= (prod-by-catalyzed-association Wee1 cdk1p3-cycA Wee1p1) 4)
	(catalyzed-association-reaction Wee1 cdk1p3-cycB Wee1p1)
	(= (need-for-catalyzed-association Wee1 cdk1p3-cycB Wee1p1) 2)
	(= (need-for-catalyzed-association cdk1p3-cycB Wee1 Wee1p1) 3)
	(= (prod-by-catalyzed-association Wee1 cdk1p3-cycB Wee1p1) 4)
	(= (num-subs) 0)
	(= (duration-association-reaction AP2 gE-c AP2-gE-c) 0.9)
	(= (duration-synthesis-reaction AP2-gE-c Ecadherin) 4.5)
	(= (duration-catalyzed-association-reaction APC Plk1 APCp1) 2.1)
	(= (duration-association-reaction c-Abl pRb c-Abl-pRb) 0.8)
	(= (duration-association-reaction c-Abl pRbp1 c-Abl-pRbp1) 1.0)
	(= (duration-catalyzed-association-reaction cdc25C cdk1p3-cycA cdc25Cp1) 1.8)
	(= (duration-catalyzed-association-reaction cdc25C cdk1p3-cycB cdc25Cp1) 2.2)
	(= (duration-catalyzed-association-reaction cdc25C Chk1 cdc25Cp2) 2.2)
	(= (duration-catalyzed-association-reaction cdc25C C-TAK1 cdc25Cp2) 2.3)
	(= (duration-catalyzed-association-reaction cdc25Cp1 Chk1 cdc25Cp1p2) 2.0)
	(= (duration-catalyzed-association-reaction cdc25Cp1 C-TAK1 cdc25Cp1p2) 2.2)
	(= (duration-catalyzed-association-reaction cdc25Cp2 cdk1p3-cycA cdc25Cp1p2) 1.9)
	(= (duration-catalyzed-association-reaction cdc25Cp2 cdk1p3-cycB cdc25Cp1p2) 2.3)
	(= (duration-catalyzed-association-reaction cdc25Cp2 Plk1 cdc25Cp1p2) 2.3)
	(= (duration-catalyzed-association-reaction cdc25C Plk1 cdc25Cp1) 1.7)
	(= (duration-catalyzed-association-reaction cdk1 cdk7-cycH cdk1p3) 1.9)
	(= (duration-association-reaction cdk1 cks1 cdk1-cks1) 1.1)
	(= (duration-association-reaction cdk1 Gadd45 cdk1-Gadd45) 0.9)
	(= (duration-catalyzed-association-reaction cdk1p1 cdc25Cp1 cdk1) 1.7)
	(= (duration-catalyzed-association-reaction cdk1p1 cdc25Cp1p2 cdk1) 2.2)
	(= (duration-catalyzed-association-reaction cdk1p1 cdk7-cycH cdk1p1p3) 1.7)
	(= (duration-association-reaction cdk1p1 cks1 cdk1p1-cks1) 1.1)
	(= (duration-association-reaction cdk1p1 Gadd45 cdk1p1-Gadd45) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdc25Cp1 cdk1p1) 1.8)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdc25Cp1 cdk1p2) 1.8)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdc25Cp1p2 cdk1p1) 2.1)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdc25Cp1p2 cdk1p2) 2.0)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdk7-cycH cdk1p1p2p3) 1.6)
	(= (duration-association-reaction cdk1p1p2 cks1 cdk1p1p2-cks1) 0.9)
	(= (duration-association-reaction cdk1p1p2 Gadd45 cdk1p1p2-Gadd45) 0.8)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1 cdk1p1p3) 1.8)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1 cdk1p2p3) 2.2)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1p2 cdk1p1p3) 2.2)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1p2 cdk1p2p3) 2.0)
	(= (duration-association-reaction cdk1p1p2p3 cks1 cdk1p1p2p3-cks1) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycA cdc25Cp1 cdk1p1p3-cycA) 2.2)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycA cdc25Cp1 cdk1p2p3-cycA) 2.2)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycA cdc25Cp1p2 cdk1p1p3-cycA) 1.7)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycA cdc25Cp1p2 cdk1p2p3-cycA) 1.7)
	(= (duration-association-reaction cdk1p1p2p3 cycA cdk1p1p2p3-cycA) 0.9)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1 cdk1p1p3-cycB) 1.7)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1 cdk1p2p3-cycB) 1.6)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p1p3-cycB) 2.1)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p2p3-cycB) 1.7)
	(= (duration-association-reaction cdk1p1p2p3 cycB cdk1p1p2p3-cycB) 1.1)
	(= (duration-association-reaction cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45) 0.9)
	(= (duration-catalyzed-association-reaction cdk1p1p3 cdc25Cp1 cdk1p3) 1.7)
	(= (duration-catalyzed-association-reaction cdk1p1p3 cdc25Cp1p2 cdk1p3) 1.9)
	(= (duration-association-reaction cdk1p1p3 cks1 cdk1p1p3-cks1) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p1p3-cycA cdc25Cp1 cdk1p3-cycA) 1.8)
	(= (duration-catalyzed-association-reaction cdk1p1p3-cycA cdc25Cp1p2 cdk1p3-cycA) 2.1)
	(= (duration-association-reaction cdk1p1p3 cycA cdk1p1p3-cycA) 0.8)
	(= (duration-catalyzed-association-reaction cdk1p1p3-cycA Wee1 cdk1p1p2p3-cycA) 1.7)
	(= (duration-catalyzed-association-reaction cdk1p1p3-cycB cdc25Cp1 cdk1p3-cycB) 2.1)
	(= (duration-catalyzed-association-reaction cdk1p1p3-cycB cdc25Cp1p2 cdk1p3-cycB) 2.1)
	(= (duration-association-reaction cdk1p1p3 cycB cdk1p1p3-cycB) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p1p3-cycB Wee1 cdk1p1p2p3-cycB) 1.9)
	(= (duration-association-reaction cdk1p1p3 Gadd45 cdk1p1p3-Gadd45) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p2 cdc25Cp1 cdk1) 2.3)
	(= (duration-catalyzed-association-reaction cdk1p2 cdc25Cp1p2 cdk1) 2.0)
	(= (duration-catalyzed-association-reaction cdk1p2 cdk7-cycH cdk1p2p3) 2.2)
	(= (duration-association-reaction cdk1p2 cks1 cdk1p2-cks1) 1.0)
	(= (duration-association-reaction cdk1p2 Gadd45 cdk1p2-Gadd45) 0.9)
	(= (duration-catalyzed-association-reaction cdk1p2p3 cdc25Cp1 cdk1p3) 1.8)
	(= (duration-catalyzed-association-reaction cdk1p2p3 cdc25Cp1p2 cdk1p3) 1.8)
	(= (duration-association-reaction cdk1p2p3 cks1 cdk1p2p3-cks1) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p2p3-cycA cdc25Cp1 cdk1p3-cycA) 1.7)
	(= (duration-catalyzed-association-reaction cdk1p2p3-cycA cdc25Cp1p2 cdk1p3-cycA) 2.0)
	(= (duration-association-reaction cdk1p2p3 cycA cdk1p2p3-cycA) 1.0)
	(= (duration-catalyzed-association-reaction cdk1p2p3-cycB cdc25Cp1 cdk1p3-cycB) 1.8)
	(= (duration-catalyzed-association-reaction cdk1p2p3-cycB cdc25Cp1p2 cdk1p3-cycB) 2.2)
	(= (duration-association-reaction cdk1p2p3 cycB cdk1p2p3-cycB) 1.0)
	(= (duration-association-reaction cdk1p2p3 Gadd45 cdk1p2p3-Gadd45) 1.1)
	(= (duration-association-reaction cdk1p3 cks1 cdk1p3-cks1) 1.1)
	(= (duration-association-reaction cdk1p3 cycA cdk1p3-cycA) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p3-cycA Wee1 cdk1p2p3-cycA) 2.1)
	(= (duration-association-reaction cdk1p3 cycB cdk1p3-cycB) 0.9)
	(= (duration-catalyzed-association-reaction cdk1p3-cycB Wee1 cdk1p2p3-cycB) 2.3)
	(= (duration-association-reaction cdk1p3 Gadd45 cdk1p3-Gadd45) 1.0)
	(= (duration-catalyzed-association-reaction cdk2p1 cdk7-cycH cdk2p1p2) 2.1)
	(= (duration-association-reaction cdk2p1 cks1 cdk2p1-cks1) 1.1)
	(= (duration-association-reaction cdk2p1 cycA cdk2p1-cycA) 0.9)
	(= (duration-catalyzed-association-reaction cdk2p1-cycA cdk7-cycH cdk2p1p2-cycA) 2.1)
	(= (duration-association-reaction cdk2p1-cycA E2F13 cdk2p1-cycA-E2F13) 0.9)
	(= (duration-association-reaction cdk2p1 cycE cdk2p1-cycE) 0.8)
	(= (duration-catalyzed-association-reaction cdk2p1-cycE cdk7-cycH cdk2p1p2-cycE) 1.6)
	(= (duration-association-reaction cdk2p1 cycEp1 cdk2p1-cycEp1) 1.1)
	(= (duration-catalyzed-association-reaction cdk2p1-cycEp1 cdk7-cycH cdk2p1p2-cycEp1) 1.9)
	(= (duration-association-reaction cdk2p1p2 cks1 cdk2p1p2-cks1) 1.1)
	(= (duration-association-reaction cdk2p1p2 cycA cdk2p1p2-cycA) 0.9)
	(= (duration-association-reaction cdk2p1p2-cycA E2F13 cdk2p1p2-cycA-E2F13) 0.9)
	(= (duration-association-reaction cdk2p1p2 cycE cdk2p1p2-cycE) 0.8)
	(= (duration-association-reaction cdk2p1p2 cycEp1 cdk2p1p2-cycEp1) 1.1)
	(= (duration-catalyzed-association-reaction cdk2p2-cycB Wee1 cdk2p1p2-cycB) 1.8)
	(= (duration-catalyzed-association-reaction cdk7 cdk7-cycH cdk7p1) 1.8)
	(= (duration-association-reaction cdk7 cycH cdk7-cycH) 0.9)
	(= (duration-catalyzed-association-reaction cdk7-cycH cdk7-cycH cdk7p1-cycH) 1.6)
	(= (duration-association-reaction cdk7p1 cycH cdk7p1-cycH) 1.1)
	(= (duration-association-reaction c-Myc AP2 c-Myc-AP2) 1.0)
	(= (duration-association-reaction c-Myc Max c-Myc-Max) 1.0)
	(= (duration-catalyzed-association-reaction cycB APCp1 APCp1) 1.7)
	(= (duration-catalyzed-association-reaction DMP1 cdk46p3-cycDp1 DMP1p1) 2.3)
	(= (duration-association-reaction DMP1 cycD DMP1-cycD) 1.0)
	(= (duration-association-reaction DMP1 cycDp1 DMP1-cycDp1) 1.1)
	(= (duration-association-reaction DMP1 gp19ARF DMP1-gp19ARF) 1.1)
	(= (duration-association-reaction DMP1p1 cycD DMP1p1-cycD) 0.9)
	(= (duration-association-reaction DMP1p1 cycDp1 DMP1p1-cycDp1) 0.9)
	(= (duration-association-reaction DMP1p1 gp19ARF DMP1p1-gp19ARF) 1.0)
	(= (duration-synthesis-reaction DMP1p1-gp19ARF p19ARF) 4.4)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 c-Myc) 3.7)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 cycA) 3.6)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 cycD) 3.3)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 cycDp1) 4.2)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 cycE) 4.0)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 cycEp1) 4.5)
	(= (duration-association-reaction E2F13-DP12 gE2 E2F13-DP12-gE2) 0.9)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 p107) 4.0)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 p107p1) 4.2)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 p19ARF) 3.4)
	(= (duration-synthesis-reaction E2F13-DP12-gE2 pol) 3.7)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 c-Myc) 4.5)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 cycA) 4.0)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 cycD) 4.6)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 cycDp1) 3.7)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 cycE) 4.4)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 cycEp1) 3.7)
	(= (duration-association-reaction E2F13p1-DP12 gE2 E2F13p1-DP12-gE2) 1.0)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 p107) 3.7)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 p107p1) 4.2)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 p19ARF) 4.1)
	(= (duration-synthesis-reaction E2F13p1-DP12-gE2 pol) 4.3)
	(= (duration-association-reaction HDAC1-p107-E2F4p1-DP12 gE2 HDAC1-p107-E2F4p1-DP12-gE2) 1.1)
	(= (duration-association-reaction HDAC1-p130-E2F4p1-DP12 gE2 HDAC1-p130-E2F4p1-DP12-gE2) 1.0)
	(= (duration-association-reaction HDAC1-pRb-E2F13-DP12 gE2 HDAC1-pRb-E2F13-DP12-gE2) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F13-DP12p1 HDAC1-pRb-E2F13-DP12p1) 1.0)
	(= (duration-association-reaction HDAC1-pRb-E2F13p1-DP12 gE2 HDAC1-pRb-E2F13p1-DP12-gE2) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F4p1-DP12 HDAC1-pRb-E2F4p1-DP12) 1.0)
	(= (duration-association-reaction HDAC1-pRbp1-E2F13-DP12 gE2 HDAC1-pRbp1-E2F13-DP12-gE2) 1.0)
	(= (duration-association-reaction HDAC1-pRbp1-E2F13p1-DP12 gE2 HDAC1-pRbp1-E2F13p1-DP12-gE2) 1.1)
	(= (duration-synthesis-reaction Jun-c-Fos-gERCC1 ERCC1) 3.3)
	(= (duration-association-reaction Jun-c-Fos gERCC1 Jun-c-Fos-gERCC1) 0.9)
	(= (duration-association-reaction Jun c-Fos Jun-c-Fos) 1.0)
	(= (duration-association-reaction m1433 cdc25Cp1p2 m1433-cdc25Cp1p2) 0.8)
	(= (duration-association-reaction m1433 cdc25Cp2 m1433-cdc25Cp2) 1.1)
	(= (duration-association-reaction Mdm2 E2F13-DP12 Mdm2-E2F13-DP12) 0.8)
	(= (duration-association-reaction Mdm2 E2F13-DP12p1 Mdm2-E2F13-DP12p1) 0.9)
	(= (duration-association-reaction Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12) 0.8)
	(= (duration-association-reaction Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1) 1.1)
	(= (duration-association-reaction Mdm2 pRb Mdm2-pRb) 1.0)
	(= (duration-association-reaction Mdm2 pRbp1 Mdm2-pRbp1) 1.0)
	(= (duration-association-reaction p21 cdk2p1-cycA p21-cdk2p1-cycA) 1.1)
	(= (duration-association-reaction p21 cdk2p1-cycEp1 p21-cdk2p1-cycEp1) 1.1)
	(= (duration-association-reaction p21 cdk2p1-cycE p21-cdk2p1-cycE) 0.8)
	(= (duration-association-reaction p21 cdk2p1p2-cycA p21-cdk2p1p2-cycA) 1.1)
	(= (duration-association-reaction p21 cdk2p1p2-cycEp1 p21-cdk2p1p2-cycEp1) 1.1)
	(= (duration-association-reaction p21 cdk2p1p2-cycE p21-cdk2p1p2-cycE) 0.9)
	(= (duration-association-reaction p21 Gadd45 p21-Gadd45) 1.0)
	(= (duration-association-reaction p27 cdk2p1-cycA p27-cdk2p1-cycA) 1.0)
	(= (duration-association-reaction p27 cdk2p1-cycEp1 p27-cdk2p1-cycEp1) 1.0)
	(= (duration-association-reaction p27 cdk2p1-cycE p27-cdk2p1-cycE) 1.1)
	(= (duration-association-reaction p27 cdk2p1p2-cycA p27-cdk2p1p2-cycA) 0.9)
	(= (duration-association-reaction p27 cdk2p1p2-cycEp1 p27-cdk2p1p2-cycEp1) 1.0)
	(= (duration-association-reaction p27 cdk2p1p2-cycE p27-cdk2p1p2-cycE) 0.9)
	(= (duration-synthesis-reaction p53 c-Fos) 3.5)
	(= (duration-synthesis-reaction p53 Gadd45) 4.1)
	(= (duration-synthesis-reaction p53 Mdm2) 3.8)
	(= (duration-synthesis-reaction p53p1 c-Fos) 4.4)
	(= (duration-synthesis-reaction p53p1 Gadd45) 4.2)
	(= (duration-synthesis-reaction p53p1 Mdm2) 3.8)
	(= (duration-synthesis-reaction p53p1 p21) 4.3)
	(= (duration-synthesis-reaction p53 p21) 4.3)
	(= (duration-association-reaction p57 cdk2p1-cycA p57-cdk2p1-cycA) 0.9)
	(= (duration-association-reaction p57 cdk2p1-cycEp1 p57-cdk2p1-cycEp1) 0.9)
	(= (duration-association-reaction p57 cdk2p1-cycE p57-cdk2p1-cycE) 1.1)
	(= (duration-association-reaction p57 cdk2p1p2-cycA p57-cdk2p1p2-cycA) 0.8)
	(= (duration-association-reaction p57 cdk2p1p2-cycEp1 p57-cdk2p1p2-cycEp1) 0.9)
	(= (duration-association-reaction p57 cdk2p1p2-cycE p57-cdk2p1p2-cycE) 1.0)
	(= (duration-synthesis-reaction pRb-AP2-gE-c Ecadherin) 3.6)
	(= (duration-association-reaction pRb-AP2 gE-c pRb-AP2-gE-c) 0.9)
	(= (duration-association-reaction pRb AP2 pRb-AP2) 0.8)
	(= (duration-catalyzed-association-reaction pRb cdk46p3-cycDp1 pRbp1) 1.9)
	(= (duration-association-reaction pRb-E2F13-DP12 gE2 pRb-E2F13-DP12-gE2) 1.0)
	(= (duration-association-reaction pRb-E2F13-DP12p1 gE2 pRb-E2F13-DP12p1-gE2) 1.0)
	(= (duration-association-reaction pRb E2F13-DP12p1 pRb-E2F13-DP12p1) 1.1)
	(= (duration-association-reaction pRb E2F13-DP12 pRb-E2F13-DP12) 0.9)
	(= (duration-association-reaction pRb-E2F13p1-DP12 gE2 pRb-E2F13p1-DP12-gE2) 0.9)
	(= (duration-association-reaction pRb-E2F13p1-DP12p1 gE2 pRb-E2F13p1-DP12p1-gE2) 0.9)
	(= (duration-association-reaction pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1) 0.9)
	(= (duration-association-reaction pRb E2F13p1-DP12 pRb-E2F13p1-DP12) 1.1)
	(= (duration-association-reaction pRb-E2F4p1-DP12 gE2 pRb-E2F4p1-DP12-gE2) 1.1)
	(= (duration-synthesis-reaction pRb-Jun-c-Fos-gERCC1 ERCC1) 3.5)
	(= (duration-association-reaction pRb-Jun-c-Fos gERCC1 pRb-Jun-c-Fos-gERCC1) 1.0)
	(= (duration-association-reaction pRb-Jun c-Fos pRb-Jun-c-Fos) 0.9)
	(= (duration-association-reaction pRb Jun pRb-Jun) 0.8)
	(= (duration-synthesis-reaction pRbp1-AP2-gE-c Ecadherin) 4.4)
	(= (duration-association-reaction pRbp1-AP2 gE-c pRbp1-AP2-gE-c) 0.9)
	(= (duration-association-reaction pRbp1 AP2 pRbp1-AP2) 1.0)
	(= (duration-association-reaction pRbp1-E2F13-DP12 gE2 pRbp1-E2F13-DP12-gE2) 1.1)
	(= (duration-association-reaction pRbp1-E2F13-DP12p1 gE2 pRbp1-E2F13-DP12p1-gE2) 0.8)
	(= (duration-association-reaction pRbp1 E2F13-DP12p1 pRbp1-E2F13-DP12p1) 0.9)
	(= (duration-association-reaction pRbp1 E2F13-DP12 pRbp1-E2F13-DP12) 1.1)
	(= (duration-association-reaction pRbp1-E2F13p1-DP12 gE2 pRbp1-E2F13p1-DP12-gE2) 1.1)
	(= (duration-association-reaction pRbp1-E2F13p1-DP12p1 gE2 pRbp1-E2F13p1-DP12p1-gE2) 1.0)
	(= (duration-association-reaction pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1) 0.9)
	(= (duration-association-reaction pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12) 0.8)
	(= (duration-synthesis-reaction pRbp1-Jun-c-Fos-gERCC1 ERCC1) 4.2)
	(= (duration-association-reaction pRbp1-Jun-c-Fos gERCC1 pRbp1-Jun-c-Fos-gERCC1) 0.8)
	(= (duration-association-reaction pRbp1-Jun c-Fos pRbp1-Jun-c-Fos) 0.8)
	(= (duration-association-reaction pRbp1 Jun pRbp1-Jun) 1.0)
	(= (duration-association-reaction RPA cycA RPA-cycA) 1.1)
	(= (duration-association-reaction Skp2 cdk2p1-cycA Skp2-cdk2p1-cycA) 0.9)
	(= (duration-association-reaction Skp2 cdk2p1p2-cycA Skp2-cdk2p1p2-cycA) 0.9)
	(= (duration-association-reaction SP1 E2F13 SP1-E2F13) 1.0)
	(= (duration-association-reaction SP1 p107p1 SP1-p107p1) 1.0)
	(= (duration-association-reaction SP1 p107 SP1-p107) 0.9)
	(= (duration-catalyzed-association-reaction Wee1 cdk1p3-cycA Wee1p1) 1.9)
	(= (duration-catalyzed-association-reaction Wee1 cdk1p3-cycB Wee1p1) 2.0))

(:goal
	(and
	(preference p0A (>= (+ (available cdk1p3-Gadd45) (available Wee1p1)) 8))
	(preference p0B (>= (+ (available cdk1p3-cycA) (available cdk1p3-cks1)) 4))
	(preference p0C (>= (+ (available cdk1p3-cycB) (available p57-cdk2p1-cycEp1)) 3))
	(preference p0D (>= (+ (available p57-cdk2p1-cycE) (available cdk1p2p3-cks1)) 5))
	(preference p0E (>= (+ (available cdk1p2-cks1) (available Mdm2-E2F13-DP12)) 5))
	(preference p0F (>= (+ (available p27-cdk2p1-cycA) (available cdk1p2p3-cycA)) 4))
	(preference p0G (>= (+ (available cdk2p1-cycE) (available cdk1p1p3-cycB)) 5))
	(preference p0H (>= (+ (available cdk1p1p2p3-Gadd45) (available pRbp1-Jun-c-Fos-gERCC1)) 7))
	(preference p0I (>= (+ (available cdk2p1p2-cycEp1) (available cdk1-cks1)) 8))
	(preference p0J (>= (+ (available p21-cdk2p1p2-cycE) (available cdk1p1p2p3-cycB)) 4))
	(preference p0K (>= (+ (available cdk1p3) (available p57-cdk2p1p2-cycE)) 5))
	(preference p0L (>= (+ (available cdk1p2p3-cycB) (available cdk2p1-cycA)) 5))
	(preference p0M (>= (+ (available p21-cdk2p1-cycE) (available p27-cdk2p1p2-cycA)) 5))
	(preference p0N (>= (+ (available Skp2-cdk2p1-cycA) (available pRbp1-AP2-gE-c)) 5))
	(preference p0O (>= (+ (available p27-cdk2p1-cycEp1) (available p27-cdk2p1p2-cycE)) 6))
	(preference p0P (>= (+ (available p21-cdk2p1p2-cycA) (available p27-cdk2p1-cycE)) 8))
	(preference p0Q (>= (+ (available p57-cdk2p1p2-cycA) (available HDAC1-pRb-E2F13p1-DP12-gE2)) 3))
	(preference p0R (>= (+ (available DMP1p1-cycDp1) (available cdk1p1-cks1)) 3))))


(:constraints (and

	(preference p1A (sometime-before (> (available cdk1p2p3-cycA) 0) (> (available cdk1) 0)))
	(preference p1B (sometime-before (> (available cdk1p1p3-cycB) 0) (> (available cdk7-cycH) 0)))
	(preference p1C (sometime-before (> (available Skp2-cdk2p1-cycA) 0) (> (available E2F13p1-DP12-gE2) 0)))
	(preference p1D (sometime-before (> (available pRbp1-AP2-gE-c) 0) (> (available pRbp1) 0)))
	(preference p1E (sometime-before (> (available p21-cdk2p1p2-cycA) 0) (> (available p21) 0)))
	(preference p1F (sometime-before (> (available p27-cdk2p1-cycE) 0) (> (available cycE) 0)))
	(preference p1G (sometime-before (> (available DMP1p1-cycDp1) 0) (> (available DMP1p1) 0)))

	(preference p1H (always (= (available cdc25Cp1p2) 0)))
	(preference p1I (always (= (available cdk2p1-cycA) 0)))
	(preference p1J (always (= (available c-Fos) 0)))
	(preference p1K (always (= (available cycA) 0)))
	(preference p1L (always (= (available pRbp1-AP2) 0)))

	(preference p1M (sometime (> (available cdk1p1p3-cks1) 0)))
	(preference p1N (sometime-after (> (available cdk1p1p3-cks1) 0) (> (available cdk1p1p2p3-cycA) 0)))
	(preference p1O (sometime (> (available pRbp1-E2F13p1-DP12-gE2) 0)))
	(preference p1P (sometime-after (> (available pRbp1-E2F13p1-DP12-gE2) 0) (> (available HDAC1-pRb-E2F13-DP12-gE2) 0)))
	(preference p1Q (sometime (> (available c-Myc-AP2) 0)))
	(preference p1R (sometime-after (> (available c-Myc-AP2) 0) (> (available cdk1p1p3-cycA) 0)))
	(preference p1S (sometime (> (available p57-cdk2p1-cycA) 0)))
	(preference p1T (sometime-after (> (available p57-cdk2p1-cycA) 0) (> (available cdk2p1p2-cycB) 0)))
	(preference p1U (sometime (> (available pRb-E2F13p1-DP12p1) 0)))
	(preference p1V (sometime-after (> (available pRb-E2F13p1-DP12p1) 0) (> (available pRb-E2F13-DP12p1-gE2) 0)))
	(preference p1W (sometime (> (available AP2-gE-c) 0)))
	(preference p1X (sometime-after (> (available AP2-gE-c) 0) (> (available pRb-Jun-c-Fos-gERCC1) 0)))
	(preference p1Y (sometime (> (available HDAC1-pRb-E2F13p1-DP12p1) 0)))
	(preference p1Z (sometime-after (> (available HDAC1-pRb-E2F13p1-DP12p1) 0) (> (available pRb-Jun-c-Fos) 0)))
	(preference p1AB (sometime (> (available c-Abl-pRbp1) 0)))
	(preference p1BB (sometime-after (> (available c-Abl-pRbp1) 0) (> (available HDAC1-pRbp1-E2F13p1-DP12-gE2) 0)))))

(:metric minimize (+ (* 1.8 (is-violated p0A))
		     (* 1.6 (is-violated p0B))
		     (* 1.7 (is-violated p0C))
		     (* 1.9 (is-violated p0D))
		     (* 1.6 (is-violated p0E))
		     (* 1.8 (is-violated p0F))
		     (* 1.7 (is-violated p0G))
		     (* 1.7 (is-violated p0H))
		     (* 1.8 (is-violated p0I))
		     (* 1.9 (is-violated p0J))
		     (* 1.8 (is-violated p0K))
		     (* 1.9 (is-violated p0L))
		     (* 1.8 (is-violated p0M))
		     (* 1.8 (is-violated p0N))
		     (* 1.8 (is-violated p0O))
		     (* 1.9 (is-violated p0P))
		     (* 1.7 (is-violated p0Q))
		     (* 2.1 (is-violated p0R))
		     (* 1 (is-violated p1A))
		     (* 1 (is-violated p1B))
		     (* 1 (is-violated p1C))
		     (* 1 (is-violated p1D))
		     (* 1 (is-violated p1E))
		     (* 1 (is-violated p1F))
		     (* 1 (is-violated p1G))
		     (* 1 (is-violated p1H))
		     (* 1 (is-violated p1I))
		     (* 1 (is-violated p1J))
		     (* 1 (is-violated p1K))
		     (* 1 (is-violated p1L))
		     (* 1 (is-violated p1M))
		     (* 1 (is-violated p1N))
		     (* 1 (is-violated p1O))
		     (* 1 (is-violated p1P))
		     (* 1 (is-violated p1Q))
		     (* 1 (is-violated p1R))
		     (* 1 (is-violated p1S))
		     (* 1 (is-violated p1T))
		     (* 1 (is-violated p1U))
		     (* 1 (is-violated p1V))
		     (* 1 (is-violated p1W))
		     (* 1 (is-violated p1X))
		     (* 1 (is-violated p1Y))
		     (* 1 (is-violated p1Z))
		     (* 1 (is-violated p1AB))
		     (* 1 (is-violated p1BB))
		     (* 0.01 (total-time))
		     (num-subs)))

)
